Evidence map›Paper›PMID 34035440›Full record

ArticleCommunications biology2021

Cryo-EM structure of type 1 IP

Mariah R Baker, Guizhen Fan, Alexander B Seryshev, Melina A Agosto, Matthew L Baker, Irina I Serysheva

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 134 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Conformational landscape and clustering of human type 2 IPbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. The TRPV3 channel is a mediator of zinc influx and homeostasis in murine oocytes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Factors affecting macromolecule orientations in thin films formed in cryo-EM.Acta crystallographica. Section D, Structural biology · 2024
    Article
  12. Wound Repair and CaCells · 2024
    Review
  13. Detailed Analysis of ITPR1 Missense Variants Guides Diagnostics and Therapeutic Design.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
  14. Article
  15. Structural titration reveals CaNature communications · 2023
    Article
  16. Understanding IPCell calcium · 2023
    Review
  17. Modulation of TRPV2 by endogenous and exogenous ligands: A computational study.Protein science : a publication of the Protein Society · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mariah R Baker *Department of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA.
Guizhen Fan *Department of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA.
Alexander B SeryshevDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA.
Melina A AgostoVerna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-3647-1926
Matthew L BakerDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA.
Irina I SeryshevaDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA. irina.i.serysheva@uth.tmc.edu.ORCID 0000-0001-6266-3422
Imaging Center · USBaylor College of Medicine · USThe University of Texas Health Science Center · US

Funding

PROJECT 5 - DUKE - STRUCTURE VALIDATION AND IMPROVEMENT FOR PROTEINS AND N. ACIDSP01GM063210 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI ADAMS, PAUL DAVID · 2001 to 2021
$33.5M
Structure-Function Studies Of IP3R ChannelsR01GM072804 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2005 to 2023
$4.8M
Cilium-Associated Structures in Rod CellsR01EY026545 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WENSEL, THEODORE G · 2016 to 2024
$3.7M
Light regulation of retinal phosphoinositidesR01EY025218 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WENSEL, THEODORE G · 2016 to 2019
$1.6M
Structure-Function of PLA2g6R21NS108724 · NINDS · BOSTON MEDICAL CENTER · PI BOLOTINA, VICTORIA M, SERYSHEVA, IRINA I · 2018 to 2019
$476k
Regulation of IP3R channel in apoptosisR21NS106968 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2018 to 2019
$424k
NEI NIH HHS R01 EY025218NEI NIH HHS R01 EY026545NIGMS NIH HHS P01 GM063210NIGMS NIH HHS R01 GM072804NINDS NIH HHS R21 NS106968NINDS NIH HHS R21 NS108724
6 · The paper itself

Abstract

Type 1 inositol 1,4,5-trisphosphate receptor (IP

Indexed as

AnimalsCalcium ChannelsCryoelectron MicroscopyInositol 1,4,5-Trisphosphate ReceptorsLipid BilayersPhosphatidylcholinesProtein ConformationProtein DomainsProtein Structure, SecondaryRatsCalcium ChannelsInositol 1,4,5-Trisphosphate ReceptorsItpr1 protein, ratLipid BilayersPhosphatidylcholines

Identifiers

PMID34035440
PMCPMC8149723
OpenAlexW3164574100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.