ArticleNature communications2021
Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 1 of them a synthesis that pooled it.
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Who cites it
86 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Efficacy and mechanisms of repeated closed-loop auditory exposure during slow-wave sleep for internet gaming disorder.Molecular psychiatry · 2025Trial
- Sleep loss disrupts the neural signature of successful learning.Cerebral cortex (New York, N.Y. : 1991) · 2023Trial
- Sleep forms flexible context representations in toddlers.Nature communications · 2026Article
- Slow Oscillation-Sleep Spindle Coupling Is Associated With Expectancy Measures of Fear Extinction Retention in Trauma-Exposed Individuals.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Human brain-wide activation of sleep rhythms.eLife · 2026Article
- Theta oscillations tag episodic memories for sleep-dependent consolidation.PLoS biology · 2026Article
- EEG-based classification models reveal differential neural processing of words and images.bioRxiv : the preprint server for biology · 2026Article
- Reactivation during sleep segregates the neural representations of episodic memories.bioRxiv : the preprint server for biology · 2026Article
- Article
- Sleep strengthens successor representations of learned sequences in humans.PLoS biology · 2026Article
- Auditory-evoked changes in slow oscillations and spindles correlate with memory consolidation in children with epilepsy and controls.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Article
- Memory consolidation during sleep: a facilitator of new learning?Neuropsychologia · 2026Review
- Respiration Shapes the Neural Dynamics of Successful Remembering in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The effects of targeted reactivation on memories cued once or multiple times during a nap.Neuropsychologia · 2025Article
- SLEEP AND NEURODEGENERATION: EXAMINING POTENTIAL PHYSIOLOGICAL MECHANISMS.Current sleep medicine reports · 2025Article
- Does overnight memory consolidation support next-day learning?Cognition · 2025Article
- Manipulating memory processing during sleep to explore the critical duration of reactivation events.Neuropsychologia · 2025Article
- Slow-wave sleep and REM sleep differentially contribute to memory representational transformation.Communications biology · 2025Article
- Stimulating the Stimulated Cortex-Frontocortical Anodal Electric Stimulation Combined With Closed-Loop Acoustic Stimulation During Sleep Impairs Memory in Subjects With High Cognitive Ability.The European journal of neuroscience · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Sleep is thought to support memory consolidation via reactivation of prior experiences, with particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) gating the information flow between relevant brain areas. However, empirical evidence for a role of endogenous memory reactivation (i.e., without experimentally delivered memory cues) for consolidation in humans is lacking. Here, we devised a paradigm in which participants acquired associative memories before taking a nap. Multivariate decoding was then used to capture endogenous memory reactivation during non-rapid eye movement (NREM) sleep in surface EEG recordings. Our results reveal reactivation of learning material during SO-spindle complexes, with the precision of SO-spindle coupling predicting reactivation strength. Critically, reactivation strength (i.e. classifier evidence in favor of the previously studied stimulus category) in turn predicts the level of consolidation across participants. These results elucidate the memory function of sleep in humans and emphasize the importance of SOs and spindles in clocking endogenous consolidation processes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.