Evidence map›Paper›PMID 34034769›Full record

Observational studyNutrition journal2021

Nutritional screening based on objective indices at admission predicts in-hospital mortality in patients with COVID-19.

Feier Song, Huan Ma, Shouhong Wang, Tiehe Qin, Qing Xu, Huiqing Yuan, Fei Li, Zhonghua Wang, Youwan Liao, Xiaoping Tan and 3 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Nutrition journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  3. Clinical significance of prognostic nutrition index in hospitalized patients with COVID-19: Results from single-center experience with systematic review and meta-analysis.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Feier Song *Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Huan Ma *Department of Cardiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Cardiovascular Institute, Guangzhou, 510080, China.
Shouhong Wang *Department of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China.
Tiehe QinDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China.
Qing XuDepartment of Emergency Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Huiqing YuanDepartment of Respiratory and Critical Care Medicine, the First People's Hospital of Shaoguan, Shaoguan, 512000, China.
Fei LiDepartment of Emergency, the First Affiliated Hospital of Jingzhou, Jingzhou, 434000, China.
Zhonghua WangDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China.
Youwan LiaoDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China.
Xiaoping TanDepartment of Gastroenterology, the First Affiliated Hospital of Yangtze University, Jingzhou, 434000, China.
Xiuchan SongDepartment of Critical Care Medicine, Dongguan Eighth People's Hospital, Dongguan Children's Hospital, Dongguan, 523000, China. songxiuchan0769@163.com.
Qing ZhangDepartment of Gastroenterology, the First Affiliated Hospital of Yangtze University, Jingzhou, 434000, China. zqcn@qq.com.
Daozheng HuangDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, China. hdzdoctor@139.com.
Guangdong Academy of Medical Sciences · CNGuangdong Provincial People's Hospital · CNYangtze University · CNDongguan People’s Hospital · CNFirst People's Hospital of Jingzhou · CNShanghai Jiao Tong University · CNShaoguan Railway Hospital · CN

Funding

National Clinical Key Specialty Construction Project of China 2012-649National Clinical Key Specialty Construction Project of China 2013-544
6 · The paper itself

Abstract

backgroundCould nutritional status serve as prognostic factors for coronavirus disease 2019 (COVID-19)? The present study evaluated the clinical and nutritional characteristics of COVID-19 patients and explored the relationship between risk for malnutrition at admission and in-hospital mortality.

methodsA retrospective, observational study was conducted in two hospitals in Hubei, China. Confirmed cases of COVID-19 were typed as mild/moderate, severe, or critically ill. Clinical data and in-hospital death were collected. The risk for malnutrition was assessed using the geriatric nutritional risk index (GNRI), the prognostic nutritional index (PNI), and the Controlling Nutritional Status (CONUT) via objective parameters at admission.

resultsTwo hundred ninety-five patients were enrolled, including 66 severe patients and 41 critically ill patients. Twenty-five deaths were observed, making 8.47% in the whole population and 37.88% in the critically ill subgroup. Patients had significant differences in nutrition-related parameters and inflammatory biomarkers among three types of disease severity. Patients with lower GNRI and PNI, as well as higher CONUT scores, had a higher risk of in-hospital mortality. The receiver operating characteristic curves demonstrated the good prognostic implication of GNRI and CONUT score. The multivariate logistic regression showed that baseline nutritional status, assessed by GNRI, PNI, or CONUT score, was a prognostic indicator for in-hospital mortality.

conclusionsDespite variant screening tools, poor nutritional status was associated with in-hospital death in patients infected with COVID-19. This study highlighted the importance of nutritional screening at admission and the new insight of nutritional monitoring or therapy.

Indexed as

Hospital MortalityNutritional StatusNutrition AssessmentSARS-CoV-2AdultAgedChinaComorbidityCOVID-19Critical IllnessFemaleHumansMaleMalnutritionMiddle AgedPrognosisCoronavirusCOVID-19MalnutritionMortalityNutrition

Identifiers

PMID34034769
PMCPMC8145188
OpenAlexW3121020200

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.