Evidence map›Paper›PMID 34034687›Full record

ArticleBMC pregnancy and childbirth2021

High mortality rate of obstetric critically ill women in Rwanda and its predictability.

Alcade Rudakemwa, Amyl Lucille Cassidy, Théogène Twagirumugabe

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alcade RudakemwaRuhengeri Referral Hospital , North Province, Ruhengeri, Rwanda. rudakal@gmail.com.ORCID http://orcid.org/0000-0002-5945-6761
Amyl Lucille CassidyDepartment of Anesthesiology, Wake Forest University School of Medicine, North Carolina, Winston-Salem, USA.
Théogène TwagirumugabeCollege of Medicine and Health Sciences, University of Rwanda, University Teaching Hospital of Butare, Butare, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReasons for admission to intensive care units (ICUs) for obstetric patients vary from one setting to another. Outcomes from ICU and prediction models are not well explored in Rwanda owing to lack of appropriate scores. This study aimed to assess reasons for admission and accuracy of prediction models for mortality of obstetric patients admitted to ICUs of two public tertiary hospitals in Rwanda.

methodsWe prospectively collected data from all obstetric patients admitted to the ICUs of the two public tertiary hospitals in Rwanda from March 2017 to February 2018 to identify reasons for admission, demographic and clinical characteristics, outcome including death and its predictability by both the Modified Early Obstetric Warning Score (MEOWS) and quick Sequential Organ Failure Assessment (qSOFA). We analysed the accuracy of mortality prediction models by MEOWS or qSOFA by using logistic regression adjusting for factors associated with mortality. Area under the Receiver Operating characteristic (AUROC) curves is used to show the predicting capacity for each individual tool.

resultsObstetric patients (n = 94) represented 12.8 % of all 747 ICU admissions which is 1.8 % of all 4.999 admitted women for pregnancy or labor. Sepsis (n = 30; 31.9 %) and obstetric haemorrhage (n = 24; 25.5 %) were the two commonest reasons for ICU admission. Overall ICU mortality for obstetric patients was 54.3 % (n = 51) with average length of stay of 6.6 ± 7.525 days. MEOWS score was an independent predictor of mortality (adjusted (a)OR 1.25; 95 % CI 1.07-1.46) and so was qSOFA score (aOR 2.81; 95 % CI 1.25-6.30) with an adjusted AUROC of 0.773 (95 % CI 0.67-0.88) and 0.764 (95 % CI 0.65-0.87), indicating fair accuracy for ICU mortality prediction in these settings of both MEOWS and qSOFA scores.

conclusionsSepsis and obstetric haemorrhage were the commonest reasons for obstetric admissions to ICU in Rwanda. MEOWS and qSOFA scores could accurately predict ICU mortality of obstetric patients in resource-limited settings, but larger studies are needed before a recommendation for their use in routine practice in similar settings.

Indexed as

Hospital MortalityMaternal MortalityAdultCause of DeathCritical IllnessFemaleHospitals, UniversityHumansIntensive Care UnitsLength of StayProspective StudiesRwandaSepsisYoung AdultCritical careIntensive care unitMaternal mortality predictionObstetrics

Identifiers

PMID34034687
PMCPMC8144868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.