ArticleProceedings. Biological sciences2021
Host-pathogen immune feedbacks can explain widely divergent outcomes from similar infections.
Article in Proceedings. Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Adaptation of plateau frog peptide: From antimicrobial to angiogenic and proliferative functions.Journal of advanced research · 2026Article
- Shielded by the dead: how killed bacteria shape the dynamics and evolution of innate immunity.bioRxiv : the preprint server for biology · 2026Article
- Pathogen growth and virulence dynamics drive the host evolution against coinfections.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- A Trade-Off Between Antimicrobial Peptide Resistance and Sensitivity to Host Immune Effectors inEvolutionary applications · 2025Article
- Dose-dependent interaction of parasites with tiers of host defense predicts "wormholes" that prolong infection at intermediate inoculum sizes.PLoS computational biology · 2024Article
- The role of uncertainty and negative feedback loops in the evolution of induced immune defenses.G3 (Bethesda, Md.) · 2024Article
- Immunological feedback loops generate parasite persistence thresholds that explain variation in infection duration.Proceedings. Biological sciences · 2024Article
- A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host.PLoS pathogens · 2024Article
- Article
- Virulence decomposition for bifurcating infections.Proceedings. Biological sciences · 2023Article
- Temperature modifies trait-mediated infection outcomes in aPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Article
- Decomposing virulence to understand bacterial clearance in persistent infections.Nature communications · 2022Article
- A single mating is sufficient to induce persistent reduction of immune defense in mated female Drosophila melanogaster.Journal of insect physiology · 2022Article
- Inherent constraints on a polyfunctional tissue lead to a reproduction-immunity tradeoff.BMC biology · 2022Article
- Balancing sensitivity, risk, and immunopathology in immune regulation.Current opinion in insect science · 2022Review
- The evolution of powerful yet perilous immune systems.Trends in immunology · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A long-standing question in infection biology is why two very similar individuals, with very similar pathogen exposures, may have very different outcomes. Recent experiments have found that even isogenic
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.