ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2021
Source imaging of seizure onset predicts surgical outcome in pediatric epilepsy.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Accuracy of Machine Learning in Detecting Pediatric Epileptic Seizures: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Combining interictal and ictal low-density EEG source imaging to delineate the epileptogenic zone in young children.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Generalized epileptic discharges leading into focal onset seizure: GOFE seizures as the initial diagnosis of epilepsy.Journal of neurology · 2025Article
- Interictal EEG source connectivity to localize the epileptogenic zone in patients with drug-resistant epilepsy: A machine learning approach.Epilepsia · 2024Article
- Sleep Spindle Generation Before and After Epilepsy Surgery: A Source Imaging Study in Children with Drug-Resistant Epilepsy.Brain topography · 2024Article
- Low-density scalp electrical source imaging of the ictal onset zone network using source coherence maps.Frontiers in neurology · 2024Article
- Virtual implantation using conventional scalp EEG delineates seizure onset and predicts surgical outcome in children with epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Article
- SEEG in 3D: Interictal Source Localization From Intracerebral Recordings.Frontiers in neurology · 2022Article
- Case Report: Laser Ablation Guided by State of the Art Source Imaging Ends an Adolescent's 16-Year Quest for Seizure Freedom.Frontiers in human neuroscience · 2022Article
- Localizing the Epileptogenic Zone with Novel Biomarkers.Seminars in pediatric neurology · 2021Review
- Changes in the Functional Brain Network of Children Undergoing Repeated Epilepsy Surgery: An EEG Source Connectivity Study.Diagnostics (Basel, Switzerland) · 2021Article
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Abstract
objectiveTo assess whether ictal electric source imaging (ESI) on low-density scalp EEG can approximate the seizure onset zone (SOZ) location and predict surgical outcome in children with refractory epilepsy undergoing surgery.
methodsWe examined 35 children with refractory epilepsy. We dichotomized surgical outcome into seizure- and non-seizure-free. We identified ictal onsets recorded with scalp and intracranial EEG and localized them using equivalent current dipoles and standardized low-resolution magnetic tomography (sLORETA). We estimated the localization accuracy of scalp EEG as distance of scalp dipoles from intracranial dipoles. We also calculated the distances of scalp dipoles from resection, as well as their resection percentage and compared between seizure-free and non-seizure-free patients. We built receiver operating characteristic curves to test whether resection percentage predicted outcome.
resultsResection distance was lower in seizure-free patients for both dipoles (p = 0.006) and sLORETA (p = 0.04). Resection percentage predicted outcome with a sensitivity of 57.1% (95% CI, 34-78.2%), a specificity of 85.7% (95% CI, 57.2-98.2%) and an accuracy of 68.6% (95% CI, 50.7-83.5%) (p = 0.01).
conclusionIctal ESI performed on low-density scalp EEG can delineate the SOZ and predict outcome. SIGNIFICANCE: Such an application may increase the number of children who are referred for epilepsy surgery and improve their outcome.
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