Evidence map›Paper›PMID 34033964›Full record

ArticleThe journal of pain2021

A Mediation Appraisal of Catastrophizing, Pain-Related Outcomes, and Race in Adults With Knee Osteoarthritis.

Dottington Fullwood, Rebecca N Gomez, Zhiguang Huo, Josue S Cardoso, Emily J Bartley, Staja Q Booker, Keesha L Powell-Roach, Alisa J Johnson, Kimberly T Sibille, Adriana S Addison and 5 more

Open access · greenAbstract read
In one paragraph

Article in The journal of pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. A Systematic Review of Pain Catastrophizing and Chronic Musculoskeletal Pain.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Dottington FullwoodUniversity of Florida, Department of Aging and Geriatric Research, Gainesville, Florida.
Rebecca N GomezUniversity of Florida, College of Nursing, Gainesville, Florida.
Zhiguang HuoUniversity of Florida, Department of Biostatistics, Gainesville, Florida.
Josue S CardosoPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, Florida.
Emily J BartleyUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, Alabama.
Staja Q BookerUniversity of Florida, College of Nursing, Gainesville, Florida.
Keesha L Powell-RoachUniversity of Florida, College of Nursing, Gainesville, Florida.
Alisa J JohnsonUniversity of Florida, Department of Aging and Geriatric Research, Gainesville, Florida.
Kimberly T SibilleUniversity of Florida, Department of Aging and Geriatric Research, Gainesville, Florida.
Adriana S AddisonUniversity of Florida, Community Dentistry and Behavioral Science, Gainesville, Florida.
Burel R GoodinUniversity of Florida, Community Dentistry and Behavioral Science, Gainesville, Florida.
Roland StaudUniversity of Florida, Department of Medicine, Gainesville, Florida.
David T ReddenUniversity of Alabama at Birmingham, Department of Biostatistics, Birmingham, Alabama.
Roger B FillingimPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, Florida; University of Alabama at Birmingham, Department of Psychology, Birmingham, Alabama.
Ellen L TerryUniversity of Florida, College of Nursing, Gainesville, Florida; University of Alabama at Birmingham, Department of Psychology, Birmingham, Alabama.
University of Florida · USUniversity of Alabama at Birmingham · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
Ethnic Differences in Responses to Painful StimuliR37AG033906 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2014 to 2023
$12.9M
The University of Florida Jacksonville Aging Studies Center (JAX-ASCENT)R33AG056540 · NIA · UNIVERSITY OF FLORIDA · PI ANTON, STEPHEN D, PAHOR, MARCO · 2017 to 2021
$3.8M
Health Disparities in Osteoarthritis: Biological Aging, Stress, and Pain - Modulation by Resilience FactorsR01AG054370 · NIA · UNIVERSITY OF FLORIDA · PI SIBILLE, KIMBERLY THERESA · 2016 to 2020
$3.4M
UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Neural mechanisms underlying psychosocial contributions to ethnic group differences in painK22NS102334 · NINDS · UNIVERSITY OF FLORIDA · PI TERRY, ELLEN L. · 2018 to 2022
$854k
Adaptability and Resilience in Aging Adults (ARIAA)R00AG052642 · NIA · UNIVERSITY OF FLORIDA · PI BARTLEY, EMILY J. · 2018 to 2020
$741k
Contributions of biopsychosocial factors in sickle cell disease painK01HL153210 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROACH, KEESHA L. · 2020 to 2023
$537k
Investigating Movement-evoked Pain in osteoArthritic Conditions (IMPACT): An Observational Study to Inform Culturally-Tailored Intervention DevelopmentK23AR076463 · NIAMS · UNIVERSITY OF FLORIDA · PI BOOKER, STAJA · 2020 to 2022
$379k
NCATS NIH HHS UL1 TR001417NCATS NIH HHS UL1 TR001427NHLBI NIH HHS K01 HL153210NIAMS NIH HHS K23 AR076463NIA NIH HHS R00 AG052642NIA NIH HHS R01 AG054370NIA NIH HHS R33 AG056540NIA NIH HHS R37 AG033906NINDS NIH HHS K22 NS102334NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

The current cross-sectional study investigates whether pain catastrophizing mediates the relationship between ethnicity/race and pain, disability and physical function in individuals with knee osteoarthritis. Furthermore, this study examined mediation at 2-year follow-up. Participants included 187 community-dwelling adults with unilateral or bilateral knee pain who screened positive for knee osteoarthritis. Participants completed several self-reported pain-related measures and pain catastrophizing subscale at baseline and 2-year follow-up. Non-Hispanic Black (NHB) adults reported greater pain, disability, and poorer functional performance compared to their non-Hispanic White (NHW) counterparts (Ps < .05). NHB adults also reported greater catastrophizing compared to NHW adults. Mediation analyses revealed that catastrophizing mediated the relationship between ethnicity/race and pain outcome measures. Specifically, NHB individuals reported significantly greater pain and disability, and exhibited lower levels of physical function, compared to NHW individuals, and these differences were mediated by higher levels of catastrophizing among NHB persons. Catastrophizing was a significant predictor of pain and disability 2-years later in both ethnic/race groups. These results suggest that pain catastrophizing is an important variable to consider in efforts to reduce ethnic/race group disparities in chronic pain. The findings are discussed in light of structural/systemic factors that may contribute to greater self-reports of pain catastrophizing among NHB individuals. PERSPECTIVE: The current study examines whether pain catastrophizing mediates the relationship between ethnicity/race and OA-related pain, disability, and functional impairment at baseline and during a 2-year follow-up period in non-Hispanic Black and non-Hispanic White adults with knee pain. These results point to the need for interventions that target pain catastrophizing.

Indexed as

AgedBlack or African AmericanCatastrophizationChronic PainCross-Sectional StudiesFollow-Up StudiesHumansMaleMiddle AgedOsteoarthritis, KneeUnited StatesWhite Peoplechronic paindisabilityethnicity/raceknee osteoarthritisPain catastrophizing

Identifiers

PMID34033964
PMCPMC8915407
OpenAlexW3164868975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.