ArticlePLoS neglected tropical diseases2021
Associations between infection intensity categories and morbidity prevalence in school-age children are much stronger for Schistosoma haematobium than for S. mansoni.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gender-related differences in prevalence, intensity and associated risk factors of Schistosoma infections in Africa: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- High prevalence of urogenital schistosomiasis among schoolchildren in an irrigated area in Gezira State, Sudan: a brief report.Parasitology research · 2026Article
- Unravelling the true biopsychosocial impact of schistosomiasis.Trends in parasitology · 2026Review
- Bayesian machine learning enables discovery of risk factors for hepatosplenic multimorbidity related to schistosomiasis.Nature communications · 2026Article
- Association between Schistosoma mansoni infection and fecal occult blood in schoolchildren in Mbita, Suba North sub-county, western Kenya.Tropical medicine and health · 2026Article
- Schistosomiasis in Yemen: Focal Persistence, Possible Resurgence, and Challenges to Elimination.Research and reports in tropical medicine · 2026Review
- Prevalence, intensity, and risk factors of schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions.PLoS neglected tropical diseases · 2025Article
- Epidemiological burden of schistosomiasis among schoolchildren in conflict-stricken mesoendemic districts of Yemen: A decade after national mapping.PLoS neglected tropical diseases · 2025Article
- The relationship between expelled eggs, morbidity and age in a Schistosoma mansoni endemic setting in Uganda: Implications for current elimination policies.PLoS neglected tropical diseases · 2025Article
- Schistosomiasis Among Schoolchildren in Amd District of Hadhramout Governorate, East of Yemen: A Hotspot forResearch and reports in tropical medicine · 2025Article
- Urogenital schistosomiasis among school children in northwestern Tanzania: Prevalence, intensity of infection, associated factors, and pattern of urinary tract morbidities.Parasite epidemiology and control · 2024Article
- Predicting Schistosomiasis Intensity in Africa: A Machine Learning Approach to Evaluate the Progress of WHO Roadmap 2030.The American journal of tropical medicine and hygiene · 2024Article
- Urogenital schistosomiasis among adult male population in an endemic area of southern Tanzania: a descriptive cross-sectional study.BMJ open · 2024Article
- The short-term impact ofProceedings. Biological sciences · 2024Article
- The role of point-of-care ultrasound in the assessment of schistosomiasis-induced liver fibrosis: A systematic scoping review.PLoS neglected tropical diseases · 2024Article
- Harnessing Schistosoma-associated metabolite changes in the human host to identify biomarkers of infection and morbidity: Where are we and what should we do next?PLoS neglected tropical diseases · 2024Review
- Validation of artificial intelligence-based digital microscopy for automated detection of Schistosoma haematobium eggs in urine in Gabon.PLoS neglected tropical diseases · 2024Article
- Modelling morbidity for neglected tropical diseases: the long and winding road from cumulative exposure to long-term pathology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Two-stage automated diagnosis framework for urogenital schistosomiasis in microscopy images from low-resource settings.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Characterization of tungiasis infection and morbidity using thermography in Kenya revealed higher disease burden during COVID-19 school closures.Infectious diseases of poverty · 2023Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWorld Health Organization (WHO) guidelines for measuring global progress in schistosomiasis control classify individuals with Schistosoma spp. infections based on the concentration of excreted eggs. We assessed the associations between WHO infection intensity categories and morbidity prevalence for selected S. haematobium and S. mansoni morbidities in school-age children. METHODOLOGY: A total of 22,488 children aged 6-15 years from monitoring and evaluation cohorts in Burkina Faso, Mali, Niger, Uganda, Tanzania, and Zambia from 2003-2008 were analyzed using Bayesian logistic regression. Models were utilized to evaluate associations between intensity categories and the prevalence of any urinary bladder lesion, any upper urinary tract lesion, microhematuria, and pain while urinating (for S. haematobium) and irregular hepatic ultrasound image pattern (C-F), enlarged portal vein, laboratory-confirmed diarrhea, and self-reported diarrhea (for S. mansoni) across participants with infection and morbidity data. PRINCIPAL
findingsS. haematobium infection intensity categories possessed consistent morbidity prevalence across surveys for multiple morbidities and participants with light infections had elevated morbidity levels, compared to negative participants. Conversely, S. mansoni infection intensity categories lacked association with prevalence of the morbidity measures assessed. CONCLUSIONS/SIGNIFICANCE: Current status infection intensity categories for S. haematobium were associated with morbidity levels in school-age children, suggesting urogenital schistosomiasis morbidity can be predicted by an individual's intensity category. Conversely, S. mansoni infection intensity categories were not consistently indicative of childhood morbidity at baseline or during the first two years of a preventive chemotherapy control program.
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