Evidence map›Paper›PMID 34033286›Full record

ArticleArchives of endocrinology and metabolism2021

Body composition, but not insulin resistance, influences postprandial lipemia in patients with Turner's syndrome.

Rodrigo de Azeredo Siqueira, Aluana Santana Carlos, Joana Costa d'Avila, Adalgiza Mafra Moreno, Estela Luz Alves, Maria Lucia Fleiuss de Farias, Laura Maria C Mendonça, Marilia Martins Guimarães

Open access · diamondAbstract read
In one paragraph

Article in Archives of endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rodrigo de Azeredo SiqueiraLaboratório de Pesquisa Pré-Clínica, Faculdade de Medicina, Universidade de Nova Iguaçu, Nova Iguaçu, RJ, Brasil, rodrigoendocrinologista@gmail.com.
Aluana Santana CarlosLaboratório de Pesquisa Pré-Clínica, Faculdade de Medicina, Universidade de Nova Iguaçu, Nova Iguaçu, RJ, Brasil.
Joana Costa d'AvilaLaboratório de Pesquisa Pré-Clínica, Faculdade de Medicina, Universidade de Nova Iguaçu, Nova Iguaçu, RJ, Brasil, joanacpdavila@gmail.com.
Adalgiza Mafra MorenoLaboratório de Pesquisa Pré-Clínica, Faculdade de Medicina, Universidade de Nova Iguaçu, Nova Iguaçu, RJ, Brasil.
Estela Luz AlvesDepartamento de Endocrinologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Maria Lucia Fleiuss de FariasDepartamento de Endocrinologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Laura Maria C MendonçaDepartamento de Reumatologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Marilia Martins GuimarãesDepartamento de Endocrinologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro · BRUniversidade Iguaçu · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to examine the influence of body composition and insulin resistance on the magnitude of postprandial lipemia in patients with Turner's syndrome receiving oral versus transdermal estrogen replacement.

methodsTwenty-five patients with Turner's syndrome receiving oral or transdermal estrogen replacement were evaluated for body mass index, waist-to-hip and waist-to-height ratios, fasting glycemia, insulin, body composition (dual-energy X-ray absorptiometry), and postprandial lipid metabolism. For statistical analysis, we used parametric tests to compare numeric variables between the two subgroups.

resultsWe observed no difference in postprandial triglyceride levels between patients receiving oral versus transdermal hormone replacement therapy. The postprandial triglycerides increment correlated positively with the percentage of total fat mass (p=0.02) and android fat mass (p=0.02) in the transdermal group. In the oral estrogen group, a positive correlation was observed between the increment in postprandial triglycerides and waist-to-hip (p=0.15) and waist-to-height (p=0.009) ratios. No association was observed between the estrogen replacement route and insulin resistance evaluated by the homeostatic model assessment-insulin resistance (HOMA-IR) index (p=0.19 and p=0.65 for the oral and transdermal groups, respectively).

conclusionWe concluded that body composition and anthropometric characteristics possibly affect the extent of postprandial lipemia independently from the route of estrogen replacement.

Indexed as

HyperlipidemiasInsulin ResistanceTurner SyndromeBody CompositionEstradiolFemaleHumansInsulinEstradiolInsulinestrogen replacement therapyhormone replacement therapyHyperlipidemiainsulin resistanceTurner's syndrome

Identifiers

PMID34033286
PMCPMC10528628
OpenAlexW3082174948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.