ArticleArchives of endocrinology and metabolism2021
Role of elastography strain ratio and TIRADS score in predicting malignant thyroid nodule.
Article in Archives of endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Elastography Enhances Diagnostic Accuracy of ACR TI-RADS in Thyroid Nodule Evaluation.The Journal of clinical endocrinology and metabolism · 2026Article
- Sonoelastography in differentiating benign and malignant thyroid nodules: A histopathological correlation.Bioinformation · 2025Article
- Thyroid Nodule Characterization: Overview and State of the Art of Diagnosis with Recent Developments, from Imaging to Molecular Diagnosis and Artificial Intelligence.Biomedicines · 2024Review
- Predicting tall-cell subtype of papillary thyroid carcinomas independently with preoperative multimodal ultrasound.The British journal of radiology · 2024Article
- The role of elastography in determining the risk of malignant thyroid nodules in children.Frontiers in endocrinology · 2024Article
- Use of ultrasound elastography in differentiating benign from malignant thyroid nodules: a prospective study.Journal of diabetes and metabolic disorders · 2023Article
- Role of the elastography strain ratio using transrectal ultrasonography in the diagnosis of prostate cancer and clinically significant prostate cancer.Scientific reports · 2022Article
- Diagnostic Accuracy of Strain Ultrasound Elastography in Thyroid Lesions Compared to Fine-Needle Aspiration Cytology.Cureus · 2022Article
- Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology resultsTurkish journal of medical sciences · 2021Article
- The value of color Doppler ultrasound in the diagnosis of thyroid nodules: a systematic review and meta-analysis.Gland surgery · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveUltrasonography (US) is the most accurate and cost-effective imaging method in diagnosis of thyroid nodules. A practical thyroid imaging reporting and data system (TIRADS) for thyroid nodules has been proposed to classify nodules of the thyroid gland to solve the problem of nodule selection for fine needle aspiration cytology (FNAC). Real-time elastography and strain ratio (SR) is a method used to assess the stiffness and predict the malignancy of thyroid nodules. The objective of this study was to assess the role of elastography and SR and the TIRADS scoring system in discriminating malignant from benign thyroid nodules.
methodsFrom 2015 to 2018 at Cairo University Hospital, a series of 409 patients with thyroid nodules was referred to undergo thyroid ultrasound. Categorization of each nodule according to the TIRADS ranged from 1 to 5. The qualitative elastography score and semiquantitative SR of the nodules were evaluated. Final diagnosis was done by either post-thyroidectomy histopathological examination or US-guided FNAC.
resultsOur study included 409 patients with thyroid nodules. Their mean age was 39 ± 10 SD; 36 were males and 373 were females. There were 22 malignant nodules and 387 benign nodules. There were statistical differences between benign and malignant nodules regarding TIRADS classification, SR, anteroposterior/transverse ratio, degree of echogenicity, border, presence of calcification, and absence of halo sign (
conclusionElastography and SR proved to be of high significant value in discriminating benign from malignant nodules, so we recommend adding it to the TIRADS classification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.