Evidence map›Paper›PMID 34033224›Full record

ReviewDermatologic therapy2021

Androgenetic alopecia and COVID-19: A review of the hypothetical role of androgens.

Hamideh Moravvej, Mohammad Reza Pourani, Moein Baghani, Fahimeh Abdollahimajd

Open access · greenAbstract readReview
In one paragraph

Review in Dermatologic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Zoster Cranial Polyneuropathy in a COVID-19 Patient.The American journal of case reports · 2021
    Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hamideh MoravvejSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9425-7282
Mohammad Reza PouraniSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3222-7528
Moein BaghaniSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fahimeh AbdollahimajdSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9463-0665
Shahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) has become the most emerging health issue globally. A prompt investigation regarding disease management and treatment is crucial for decreasing the burden of the disease. Many explorations and hypotheses have been posed, but the definite treatment has not been determined for COVID-19. Recent studies described a substantial prevalence of COVID-19 and also a higher rate of morbidity and mortality in men afflicted with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The gender-related discordance in COVID-19 infection may be due to hormonal differences, socioeconomic factors, genetic susceptibility, gender-related comorbidities, and habits like alcohol consumption. On the other hand, several studies proposed that androgens could improve the immune system and have a protective role in COVID-19, and decreased levels of androgens might be associated with unsatisfactory outcomes. In the field of dermatology, androgenetic alopecia (AGA) is correlated with a hyperandrogenic state and may be related to COVID-19 severity. Furthermore, recent research has assessed the plausible association of AGA and COVID-19. In this review, we investigate all evidence on AGA and its relationship with COVID-19, including the possible role of androgens in COVID-19 severity and outcomes as well as candidate androgen-related drugs for the treatment of COVID-19.

Indexed as

AndrogensCOVID-19AlopeciaGenetic Predisposition to DiseaseHumansMaleSARS-CoV-2Androgensandrogenetic alopeciacoronavirus disease 2019COVID-19SARS-CoV-2 infectiontreatment

Identifiers

PMID34033224
PMCPMC8209856
OpenAlexW3164979464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.