SynthesisActa psychiatrica Scandinavica2021
Guidelines improve patient outcomes in specialised mental health care: A systematic review and meta-analysis.
Synthesis in Acta psychiatrica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Adherence to evidence-based treatment guidelines for depression: a systematic review.BMC psychiatry · 2025Pooled it
- Weight stigma in the preconception, pregnancy, and postpartum periods: A systematic review of women's perspectives.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Barriers and facilitators of adherence to clinical practice guidelines in Germany-A systematic review.Journal of evaluation in clinical practice · 2025Pooled it
- A systematic review of clinical psychological guidance for perinatal mental health.BMC psychiatry · 2023Pooled it
- Strategies for the implementation of clinical practice guidelines in public health: an overview of systematic reviews.Health research policy and systems · 2022Pooled it
- Guidelines improve patient outcomes in specialised mental health care: A systematic review and meta-analysis.Acta psychiatrica Scandinavica · 2021Pooled it
- The impact of a digital guideline version on schizophrenia guideline knowledge: results from a multicenter cluster-randomized controlled trial.BMC medicine · 2024Trial
- Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Mental health disorders and the treatment gap: a neglected public health challenge.Annals of medicine and surgery (2012) · 2026Article
- Impact of Psychiatric Rehabilitation on Chronicity and Health Outcomes in Mental Disorders: A Quasi-Experimental Study.Healthcare (Basel, Switzerland) · 2026Article
- What if I needed help? Population preferences for first-line mental health treatments in the post-COVID time.Frontiers in psychiatry · 2026Article
- Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations.BMC health services research · 2025Article
- Assessing TDApp: An AI-based clinical decision support system for ADHD treatment recommendations.Frontiers in psychiatry · 2025Article
- Determining the future role of clinical practice guidelines: The experience of Australia and New Zealand.The Australian and New Zealand journal of psychiatry · 2024Article
- Training approaches for the dissemination of clinical guidelines for NSSI: a quasi-experimental trial.Child and adolescent psychiatry and mental health · 2024Article
- The effect of education regarding treatment guidelines for schizophrenia and major depressive disorders on psychiatrists' hypnotic medication prescribing behavior: a multicenter study.BMC psychiatry · 2024Article
- Adolopment of clinical practice guidelines and creation of referral pathways for psychiatric conditions in Pakistan.The Lancet regional health. Southeast Asia · 2024Review
- Reducing suicides in mental healthcare: results from a 4-year follow-up implementation study in the Netherlands (SUPRANET).Frontiers in psychiatry · 2024Article
- Effect of education regarding treatment guidelines for schizophrenia and depression on the treatment behavior of psychiatrists: A multicenter study.Psychiatry and clinical neurosciences · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe uptake of evidence-based guideline recommendations appears to be challenging. In the midst of the discussion on how to overcome these barriers, the question of whether the use of guidelines leads to improved patient outcomes threatens to be overlooked. This study examined the effectiveness of evidence-based guidelines for all psychiatric disorders on patient health outcomes in specialist mental health care. All types of evidence-based guidelines, such as psychological and medication-focused guidelines, were eligible for inclusion. Provider performance was measured as a secondary outcome. Time to remission when treated with the guidelines was also examined.
methodSix databases were searched until 10 August 2020. Studies were selected, and data were extracted independently according to the PRISMA guidelines. Random effects meta-analyses were used to pool estimates across studies. Risk of bias was assessed according to the Cochrane Effective Practice and Organization of Care Review Group criteria. PROSPERO: CRD42020171311.
resultsThe meta-analysis included 18 studies (N = 5380). Guidelines showed a positive significant effect size on the severity of psychopathological symptoms at the patient level when compared to treatment-as-usual (TAU) (d = 0.29, 95%-CI = (0.19, 0.40), p < 0.001). Removal of a potential outlier gave globally the same results with Cohen's d = 0.26. Time to remission was shorter in the guideline treatment compared with TAU (HR = 1.54, 95%-CI = (1.29, 1.84), p = 0.001, n = 3).
conclusionsPatients cared for with guideline-adherent treatments improve to a greater degree and more quickly than patients treated with TAU. Knowledge on the mechanisms of change during guideline-adherent treatment needs to be developed further such that we can provide the best possible treatment to patients in routine care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.