Evidence map›Paper›PMID 34032940›Full record

ArticleAMB Express2021

Biofilm formation by Streptococcus mutans and its inhibition by green tea extracts.

Sara Moataz Zayed, Mohammad Mabrouk Aboulwafa, Abdelgawad Mohamed Hashem, Sarra Ebrahim Saleh

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. α2-3-Sialylated Glycoproteins AttenuateInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Antibiofilm and antibacterial effects ofBiomaterial investigations in dentistry · 2026
    Article
  11. Article
  12. 3 Biotech · 2025
    Review
  13. The impact ofFrontiers in dental medicine · 2025
    Article
  14. Antibiofilm activity of silver nanoparticles against Candida sp. isolated from the oral cavity.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  15. Journal of oral microbiology · 2025
    Article
  16. Review
  17. Article
  18. Inhibition of the Biofilm Formation of PlantPharmaceuticals (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sara Moataz ZayedMedical Sciences Department, Faculty of Dentistry, The British University in Egypt, Cairo, Egypt.
Mohammad Mabrouk AboulwafaMicrobiology and Immunology Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. mohammad.aboulwafa@ksiu.edu.eg.ORCID http://orcid.org/0000-0002-0828-1420
Abdelgawad Mohamed HashemMicrobiology and Immunology Department, Faculty of Pharmacy, The British University in Egypt, Cairo, Egypt.
Sarra Ebrahim SalehMicrobiology and Immunology Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Ain Shams University · EGBritish University in Egypt · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental Caries is considered one of the most existing and worldwide common diseases related to the oral cavity affecting both children and adults. Streptococcus mutans is the main cariogenic microorganism involved in the dental caries progression. Natural products such as herbal plants were found to have less side effects and economic value than those of the chemically synthesized antibiofilm agents. This study aimed to isolate Streptococcus mutans from different oral samples taken from saliva and dental plaques specimens to determine their capability for biofilm formation and to evaluate the antibiofilm activity of aqueous and alcoholic green tea extracts. The results revealed that 35, 4 and 1% of recovered dental plaque isolates exhibited strong, moderate and weak biofilm formation capabilities versus 26, 12 and 2% for those recovered from saliva. Two green tea extracts (aqueous and alcoholic) were tested for their antibiofilm formation activity against some selected S. mutans isolates. The results showed that the minimum biofilm inhibitory concentrations (MBICs) of the alcoholic and aqueous green tea extracts were in the range of 3.1 to 12.5 mg/ml and 6.5 to 50 mg/ml, respectively. Accordingly, green tea extracts can be incorporated in various oral preparations for preventing dental caries.

Indexed as

Antibiofilm activityDental cariesGreen tea extractsStreptococcus mutans

Identifiers

PMID34032940
PMCPMC8149520
OpenAlexW3165390816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.