Evidence map›Paper›PMID 34032568›Full record

ArticleeLife2021

Starvation-induced regulation of carbohydrate transport at the blood-brain barrier is TGF-β-signaling dependent.

Helen Hertenstein, Ellen McMullen, Astrid Weiler, Anne Volkenhoff, Holger M Becker, Stefanie Schirmeier

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. The Astrocyte: Metabolic Hub of the Brain.Cold Spring Harbor perspectives in biology · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Form and Function of the Vertebrate and Invertebrate Blood-Brain Barriers.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Plasticity of Carbohydrate Transport at the Blood-Brain Barrier.Frontiers in behavioral neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Helen HertensteinDepartment of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany.
Ellen McMullenInstitut für Neuro- und Verhaltensbiologie, WWU Münster, Münster, Germany.
Astrid WeilerDepartment of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany.
Anne VolkenhoffDepartment of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany.
Holger M BeckerDepartment of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-2700-6117
Stefanie SchirmeierDepartment of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-8431-9593
Technische Universität Dresden · DEUniversity of Kaiserslautern · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During hunger or malnutrition, animals prioritize alimentation of the brain over other organs to ensure its function and, thus, their survival. This protection, also-called brain sparing, is described from

Indexed as

Blood-Brain BarrierCarbohydrate MetabolismSignal TransductionStarvationAnimalsBiological TransportDrosophilaGene Expression RegulationGlucoseMembrane Transport ProteinsNeurogliarab GTP-Binding ProteinsTranscription, GeneticTransforming Growth Factor betaTrehaloseUp-RegulationGlucoseMembrane Transport Proteinsrab GTP-Binding ProteinsTransforming Growth Factor betaTrehaloseblood-brain barriercarbohydrate transportcell biologyD. melanogasterTGF-β signaling

Identifiers

PMID34032568
PMCPMC8149124
OpenAlexW3165840458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.