Evidence map›Paper›PMID 34032328›Full record

ArticleClinical transplantation2021

When is it safe to perform abdominal transplantation in patients with prior SARS-CoV-2 infection: A case series.

Yoichiro Natori, Shweta Anjan, Eric F Martin, Gennaro Selvagi, Aasith Villavicencio, Ana Coro, Lumen A Mendez-Castaner, Adela Mattiazzi, Javier Pagan, Mariella Ortigosa-Goggins and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 1 institution in 1 country.

Yoichiro NatoriMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Shweta AnjanMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Eric F MartinMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Gennaro SelvagiMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Aasith VillavicencioDepartment of Medicine, Division of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Ana CoroMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Lumen A Mendez-CastanerMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Adela MattiazziMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Javier PaganMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Mariella Ortigosa-GogginsMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
David RothMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Warren KupinMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Christopher B O'BrienMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Leopoldo R ArosemenaMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Gaetano CiancioMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
George W BurkeMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Mahmoud MorsiMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Jose M FigueiroMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Linda ChenMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Akin TekinMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Rafael MiyashiroMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Jacques SimkinsMiami Transplant Institute, Jackson Health System, Miami, FL, USA.ORCID 0000-0001-9626-0760
Lilian M AbboMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Rodrigo M ViannaMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Giselle GuerraMiami Transplant Institute, Jackson Health System, Miami, FL, USA.ORCID 0000-0002-4098-4652
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Coronavirus disease 2019(COVID-19) pandemic has negatively impacted worldwide organ transplantation. However, there is limited information on recipients transplanted after SARS-CoV-2 infection. A full understanding of this scenario is required, as transplantation is a life-saving procedure and COVID-19 remains an ongoing threat.

methodsAbdominal organ transplant recipients diagnosed with COVID-19 prior to transplantation were identified by chart review and clinical data were collected. The primary outcome was the transplant outcome including graft loss, rejection and death, and reactivation of infection post-transplant.

resultsWe identified 14 patients who received abdominal organ transplants after symptomatic PCR confirmed SARS-CoV-2 infection; four patients had a positive PCR at the time of admission for transplantation. The median time of follow-up was 79 (22-190) days. One recipient with negative PCR before transplant tested positive 9 days after transplant. One of 14 transplanted patients developed disseminated mold infection and died 86 days after transplant. During the follow-up, only one patient developed rejection; thirteen patients had favorable graft outcomes.

conclusionsWe were able to perform abdominal transplantation for patients with COVID-19 before transplant, even with positive PCR at the time of transplant. Larger studies are needed to determine the time to safe transplant after SARS-CoV-2 infection.

Indexed as

COVID-19Kidney TransplantationHospitalizationHumansSARS-CoV-2Transplant Recipientsabdominal transplantationcoronavirus disease 2019PCR

Identifiers

PMID34032328
PMCPMC8209911
OpenAlexW3164000684

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.