Evidence map›Paper›PMID 34032275›Full record

ArticleJournal of anatomy2021

High-resolution magnetic resonance and mass spectrometry imaging of the human larynx.

Ayami Ohno Kishimoto, Yo Kishimoto, Xudong Shi, Elizabeth B Hutchinson, Hua Zhang, Yatao Shi, Gisele Oliveira, Lingjun Li, Nathan V Welham, Ian J Rowland

Open access · greenAbstract read
In one paragraph

Article in Journal of anatomy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ayami Ohno KishimotoDepartment of Diagnostic Radiology, Kyoto Katsura Hospital, Kyoto, Japan.ORCID 0000-0001-5071-6515
Yo KishimotoDepartment of Otolaryngology - Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-3583-0165
Xudong ShiDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-6469-3481
Elizabeth B HutchinsonDepartment of Biomedical Engineering, University of Arizona, Tucson, AZ, USA.ORCID 0000-0002-3374-5469
Hua ZhangDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-2875-7243
Yatao ShiDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-8240-3035
Gisele OliveiraGraduate Program in Speech-Language Pathology, Touro College, Brooklyn, NY, USA.
Lingjun LiDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-0056-3869
Nathan V WelhamDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-3484-3455
Ian J RowlandDepartment of Entomology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-2282-7765
University of Wisconsin–Madison · USKyoto Katsura Hospital · JPKyoto University · JPTouro College · USUniversity of Arizona · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Project 3: Modulation of the head and neck tumor immune microenvironment by targeting the TAM family of receptorsP50CA278595 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Zachary Scott Morris · 2022 to 2026
$12.5M
Project 4: Role of Receptor Tyrosine Kinase AXL in HNSCC Therapy ResistanceP50DE026787 · NIDCR · UNIVERSITY OF WISCONSIN-MADISON · PI HARARI, PAUL M · 2016 to 2020
$10.8M
PHONOSURGICAL OPTIMIZATION CRITERIA FOR SULCUS VOCALISR01DC004428 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Nathan Welham · 2000 to 2026
$8.7M
Mass Spectrometric Studies of Neuropeptides in FeedingR01DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2006 to 2026
$6.7M
Regeneration of Multi-Layered Vocal Fold MucosaR01DC010777 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI WELHAM, NATHAN · 2010 to 2020
$5.3M
Acquisition of a High-Field Dual Source FTICR-MS for Pharmaceutical ResearchS10RR029531 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2011 to 2011
$2.1M
MULTIPLEX CHEMICAL TAGS FOR HIGH-THROUGHPUT GLYCAN AND GLYCOPEPTIDE QUANTITATION AND CHARACTERIZATIONU01CA231081 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2018 to 2020
$1.3M
In Situ Protein Characterization and Visualization in the Brains of Mouse Models for AutismR56MH110215 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI IKONOMIDOU, HRISSANTHI, LI, LINGJUN · 2017 to 2018
$752k
Anchorage-independent culture for maintaining vocal fold epithelial stem cellsR21DC017836 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI SHI, XUDONG, WELHAM, NATHAN · 2019 to 2020
$421k
NCI NIH HHS P30 CA014520NCI NIH HHS P50 CA278595NCI NIH HHS U01 CA231081NCRR NIH HHS S10 RR029531NIDCD NIH HHS R01 DC004428NIDCD NIH HHS R01 DC010777NIDCD NIH HHS R21 DC017836NIDCR NIH HHS P50 DE026787NIDDK NIH HHS R01 DK071801NIMH NIH HHS R56 MH110215
6 · The paper itself

Abstract

High-resolution, noninvasive and nondestructive imaging of the subepithelial structures of the larynx would enhance microanatomic tissue assessment and clinical decision making; similarly, in situ molecular profiling of laryngeal tissue would enhance biomarker discovery and pathology readout. Towards these goals, we assessed the capabilities of high-resolution magnetic resonance imaging (MRI) and matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) imaging of rarely reported paediatric and adult cadaveric larynges that contained pathologies. The donors were a 13-month-old male, a 10-year-old female with an infraglottic mucus retention cyst and a 74-year-old female with advanced polypoid degeneration and a mucus retention cyst. MR and molecular imaging data were corroborated using whole-organ histology. Our MR protocols imaged the larynges at 45-117 μm

Indexed as

AgedChildDiffusion Tensor ImagingFemaleHumansInfantLaryngeal MusclesLarynxMagnetic Resonance ImagingMaleMass Spectrometrydiffusion tensor imagingglycomicsmolecular imagingmucus retention cystpolypoid degenerationproteomicsReinke's oedemavocal foldwhole-larynx histology

Identifiers

PMID34032275
PMCPMC8349453
OpenAlexW3164828858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.