Evidence map›Paper›PMID 34031827›Full record

SynthesisEnvironmental science and pollution research international2021

Short-term exposure to particulate matter on heart rate variability in humans: a systematic review of crossover and controlled studies.

Fangfang Huang, Yuhan Zhao, Ping Wang, Yingfang Wang, Licheng Zhang, Yanxia Luo

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Peaks, sources, and immediate health impacts of PMJournal of exposure science & environmental epidemiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fangfang Huang *School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China.
Yuhan Zhao *School of Public Health, Capital Medical University & Beijing Municipal Key Laboratory of Clinical Epidemiology, No.10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China.
Ping WangSchool of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China.
Yingfang WangSchool of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China.
Licheng ZhangSchool of Public Health, Capital Medical University & Beijing Municipal Key Laboratory of Clinical Epidemiology, No.10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China.
Yanxia LuoSchool of Public Health, Capital Medical University & Beijing Municipal Key Laboratory of Clinical Epidemiology, No.10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China. lyx100@ccmu.edu.cn.

Funding

m of Beijing Municipal Commission of Education KM201810025008the National Natural Science Foundation of China 81773512
6 · The paper itself

Abstract

As an indicator of cardiac autonomic function, heart rate variability (HRV) has been proven to decrease after short-term exposure to particulate matters (PM) based on controlled animal studies. In this study, we conducted a systematic review to investigate short-term effects of exposure with different particle sizes on HRV in humans. Both crossover and controlled studies of human which were published prior to February 2020 were searched on four electronic databases. The HRV parameters included standard deviation of normal-to-normal intervals (SDNN), root mean square of successive normal-to-normal intervals (RMSSD), percent of normal-to-normal intervals that differ by more than 50 milliseconds (PNN50), low frequency (LF), high frequency (HF), and LF/HF. This review included 14 studies with 300 participants. The short-term effects of PM exposure on HRV in humans are inconclusive. For time-domain parameters, one study showed higher SDNN values with 2-h exposure to PM, whereas another one showed lower SDNN values. One study found RMSSD increased after PM exposure. One study found PNN50 decreased after PM exposure. For frequency-domain parameters, two studies showed LF increased with 2-h exposure to PM, and two studies showed an increase of LF/HF after PM exposure. Four studies showed lower HF values after PM exposure, whereas two studies showed higher HF values. Five studies did not find statistically significant results for any HRV parameters. We could not conclude that short-term exposure to PM can influence autonomic nervous function. The inconsistent changes of HRV in response to PM exposure may have complex mechanisms, which remains to be elucidated.

Indexed as

Autonomic Nervous SystemParticulate MatterAnimalsCross-Over StudiesHeart RateHumansParticle SizeParticulate MatterControlled studyCrossover studyHeart rate variabilityHumanParticulate matterSystematic review

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.