Evidence map›Paper›PMID 34031742›Full record

ArticleSurgical endoscopy2022

Trans-oral endoscopic thyroidectomy vestibular approach (TOETVA) for the pediatric population: a multicenter, large case series.

Oded Cohen, Ralph P Tufano, Angkoon Anuwong, Jonathon O Russell, Niddal Assadi, Gianlorenzo Dionigi, Hoon Yub Kim, Antonio Bertelli, Avi Khafif

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 6 countries.

Oded CohenARM - Center for Head and Neck Surgery and Oncology, Assuta Medical Centers, Tel Aviv, Affiliated with Ben Gurion University, Beer Seva, Israel.
Ralph P TufanoDivision of Head and Neck Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins, Baltimore, MD, USA.
Angkoon AnuwongDepartment of Surgery, Minimally Invasive Endocrine and Surgery Division, Police General Hospital, Bangkok, Thailand.
Jonathon O RussellDivision of Head and Neck Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins, Baltimore, MD, USA. jrusse41@jhmi.edu.ORCID 0000-0003-2903-9649
Niddal AssadiARM - Center for Head and Neck Surgery and Oncology, Assuta Medical Centers, Tel Aviv, Affiliated with Ben Gurion University, Beer Seva, Israel.
Gianlorenzo DionigiDepartment of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Messina, Italy.
Hoon Yub KimDepartment of Surgery, Korea University College of Medicine, Seoul, Korea.
Antonio BertelliDepartment of Surgery, Santa Casa de São Paulo Medical School, Sao Paulo, Brazil.
Avi KhafifARM - Center for Head and Neck Surgery and Oncology, Assuta Medical Centers, Tel Aviv, Affiliated with Ben Gurion University, Beer Seva, Israel.
Assuta Medical Center · ILJohns Hopkins University · USFaculdade de Ciências Médicas da Santa Casa de São Paulo · BRKorea University · KRPolice General Hospital · THUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA cervical scar has been shown to have an impact on the quality of life of children undergoing thyroid surgery. Transoral endoscopic vestibular thyroidectomy via the vestibular approach (TOETVA) offers the absence of a cutaneous incision, and has not been described to date in the pediatric population.

objectiveTo describe the first series of TOETVA in a pediatric population. PATIENTS AND

methodsA retrospective, multicenter study, including all patients > 18 years old who underwent TOETVA. Data was prospectively collected and included demographics, preoperative ultrasound, cytology and indications for surgery. Intraoperative parameters included length of surgery and complications, with final pathology and postoperative course also reviewed. TOETVA surgical success was defined as completion of surgery via this approach.

resultsForty-eight children were included. Of these, 43 (89.5%) were girls. The median age was 16 years (range 10-17). The most common indication for surgery was a benign thyroid nodule (n = 26, 54.1%). Eleven patients (22.9%) had papillary thyroid carcinoma on final pathology, of which 90.9% (10/11) were diagnosed pre-operatively based on FNA cytology. Hemithyroidectomy was performed in 36 patients (75%). All surgeries were completed endoscopically. The mean malignant tumor size was 1.4 ± 0.4 cm and all tumors were completely excised with clean margins. No permanent complications were documented. A single patient (2.1%) had transient RLN injury (1.6%, 1/60 nerves at risk). Transient hypocalcemia was documented in 4 of the 12 patients undergoing total thyroidectomy (33.3%). Transient mental nerve injury/chin hypoesthesia was documented in 2 patients (4.2%).

conclusionsTOETVA appears to be a feasible and safe approach for thyroidectomy in the pediatric population in carefully selected cases, and may be discussed with patients and parents as an alternative for the trans-cervical approach.

Indexed as

Natural Orifice Endoscopic SurgeryThyroid NeoplasmsAdolescentChildFemaleHumansMaleMouthQuality of LifeRetrospective StudiesThyroidectomypediatric thyroidectomyscarless thyroidthyroidectomyTOETVAtransoral thyroidectomyvestibular approach

Identifiers

PMID34031742
OpenAlexW3165285296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.