ArticleResearch square2021
SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence.
Open access · greenAbstract readPreprint
In one paragraph
Article in Research square, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 31 citations in OpenAlex.
Corrections and comments
- Updated by
Authors and funding
29 authors at 9 institutions in 4 countries.
Yuling HanDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.ORCID 0000-0002-6805-4094
Liuliu YangDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Tae Wan KimThe Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY 10065, USA.
Manoj S NairAaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Oliver HarschnitzThe Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY 10065, USA.
Pengfei WangAaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Jiajun ZhuDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
So Yeon KooThe Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY 10065, USA.
Xuming TangDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Lauretta A LackoDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Vasuretha ChandarDivision of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Yaron BramDivision of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Tuo ZhangGenomic Resource Core Facility, Weill Cornell Medicine, New York, NY 10065, USA.ORCID 0000-0001-5396-918X
Wei ZhangGenomic Resource Core Facility, Weill Cornell Medicine, New York, NY 10065, USA.
Feng HeGenomic Resource Core Facility, Weill Cornell Medicine, New York, NY 10065, USA.
James CaicedoDepartment of Neurology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Yaoxing HuangAaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.ORCID 0000-0001-6270-1644
Todd EvansDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.ORCID 0000-0002-7148-9849
Paul van der ValkDepartment of Pathology, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, The Netherlands.
Maarten J TitulaerDepartment of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jochem K H SpoorDepartment of Neurosurgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
Robert L FurlerDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Peter CanollDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
James E GoldmanDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Serge PrzedborskiDepartment of Neurology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Robert E SchwartzDivision of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.ORCID 0000-0002-5417-5995
David D HoAaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.ORCID 0000-0003-1627-149X
Lorenz StuderThe Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY 10065, USA.ORCID 0000-0003-0741-7987
Shuibing ChenDepartment of Surgery, Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.ORCID 0000-0002-6294-5187
Cornell University · USColumbia University · USColumbia University Irving Medical Center · USErasmus MC · NLKettering University · USAaron Diamond AIDS Research Center · USAmsterdam University Medical Centers · NLColumbia College · CAMemorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MGenetic Viral and Host Adaptations to Breach Species Barriers of HCVR01AI107301 · NIAID · PRINCETON UNIVERSITY · PI Thomas Pietschmann, Alexander Ploss · 2013 to 2026
$6.0MDirecting Fate, Subtype Identity and Survival in Human Pluripotent-Derived Midbrain Dopamine NeuronsR01NS118067 · NINDS · SLOAN-KETTERING INST CAN RESEARCH · PI BETEL, DORON, STUDER, LORENZ P. · 2021 to 2025
$3.2MProtein prenylation inhibition for the treatment of tauopathiesR01NS107442 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PRZEDBORSKI, SERGE E · 2018 to 2022
$3.1MMODELING ENTERIC NERVOUS SYSTEM DEVELOPMENT AND HIRSCHSPRUNG'S DISASE IN HUMAN PLURIPOTENT STEM CELLSR01NS099270 · NINDS · SLOAN-KETTERING INST CAN RESEARCH · PI STUDER, LORENZ P. · 2016 to 2020
$2.9MOptimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyteR01DK121072 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWARTZ, ROBERT E · 2020 to 2024
$2.6MMetallothionein 1E as a Central Regulator of Human Pancreatic Beta Cell Function and SurvivalR01DK119667 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, SHUIBING · 2019 to 2022
$2.5MDefining Immune Cell Heterogeneity in Human ALS and Mouse Model of the DiseaseR01NS117583 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PRZEDBORSKI, SERGE E · 2020 to 2024
$2.4MDiscovery of T1DM Associated Functional Variants in Human Pancreatic Beta Cell Development and SurvivalDP3DK111907 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, SHUIBING · 2016 to 2016
$2.0MModeling Hepatoblastoma using pluripotent stem cell derived hepatocyte-like cellsR01CA234614 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWARTZ, ROBERT E · 2019 to 2023
$1.9MA High Content Chemical Screen to Identify the Drug Candidates Promoting Human Beta Cell ProliferationR01DK124463 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, SHUIBING · 2020 to 2023
$1.7MA High Throughput Screening to Identify Compounds Rescuing Human Pancreatic Beta Cell Function in Diabetic ConditionsR01DK116075 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, SHUIBING · 2018 to 2020
$1.3MNCI NIH HHS P30 CA008748NCI NIH HHS R01 CA234614NIAID NIH HHS R01 AI107301NIA NIH HHS R21 AG064596NICHD NIH HHS F32 HD096810NIDDK NIH HHS DP3 DK111907NIDDK NIH HHS R01 DK116075NIDDK NIH HHS R01 DK119667NIDDK NIH HHS R01 DK121072NIDDK NIH HHS R01 DK124463NIDDK NIH HHS R03 DK117252NINDS NIH HHS R01 NS099270NINDS NIH HHS R01 NS107442NINDS NIH HHS R01 NS117583NINDS NIH HHS R01 NS118067NINDS NIH HHS R21 NS111176
Abstract
COVID-19 patients commonly present with neurological signs of central nervous system (CNS)
Indexed as
midbrain dopamineneuron senescenceSARS-CoV-2
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.