Evidence map›Paper›PMID 34031619›Full record

ArticleJournal of molecular structure2021

Chemical reactivities and molecular docking studies of parthenolide with the main protease of HEP-G2 and SARS-CoV-2.

Abdelhak Ouled Aitouna, M E Belghiti, Aslı Eşme, E Anouar, Anass Ouled Aitouna, A Zeroual, M Salah, A Chekroun, H El Alaoui El Abdallaoui, A Benharref and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular structure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdelhak Ouled AitounaLaboratory of Biomolecular Chemistry, Natural Substances and Reactivity, URAC 16, Faculty of Sciences Semlalia, Cadi Ayyad University, P.O. Box 2390, Marrakech, Morocco.
M E BelghitiLaboratory of Nernest Technology, 163 Willington Street, Sherbrook, QC J1H5C7, Canada.
Aslı EşmeDepartment of Elementary Science Education Faculty of Education Kocaeli University, Umuttepe, Kocaeli 41380, Turkey.
E AnouarChemistry Department, College of Sciences and Humanities, Prince Sattam bin Abdulaziz University, P.O. Box 83, Al Kharj 11942, Saudi Arabia.
Anass Ouled AitounaMolecular Modelling and Spectroscopy Research Team, Faculty of Science, Chouaïb Doukkali University, P.O. Box 20, El Jadida 24000, Morocco.
A ZeroualMolecular Modelling and Spectroscopy Research Team, Faculty of Science, Chouaïb Doukkali University, P.O. Box 20, El Jadida 24000, Morocco.
M SalahMolecular Modelling and Spectroscopy Research Team, Faculty of Science, Chouaïb Doukkali University, P.O. Box 20, El Jadida 24000, Morocco.
A ChekrounLaboratory of Biomolecular Chemistry, Natural Substances and Reactivity, URAC 16, Faculty of Sciences Semlalia, Cadi Ayyad University, P.O. Box 2390, Marrakech, Morocco.
H El Alaoui El AbdallaouiMolecular Modelling and Spectroscopy Research Team, Faculty of Science, Chouaïb Doukkali University, P.O. Box 20, El Jadida 24000, Morocco.
A BenharrefLaboratory of Biomolecular Chemistry, Natural Substances and Reactivity, URAC 16, Faculty of Sciences Semlalia, Cadi Ayyad University, P.O. Box 2390, Marrakech, Morocco.
N MazoirLaboratory of Plant Biotechnology and Ecosystem Valorization (LB2VE), Research Unit: Natural Resource Valorizations, Faculty of Sciences Chouaib Doukkali University, P.O. Box, El Jadida 24000, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have used bioinformatics to identify drugs for the treatment of COVID-19, using drugs already being tested for the treatment as benchmarks like Remdesivir and Chloroquine. Our findings provide further support for drugs that are already being explored as therapeutic agents for the treatment of COVID-19 and identify promising new targets that merit further investigation. In addition, the epoxidation of Parthenolide

Indexed as

DFTDocking calculationELFEpoxidationParthenolideSARS-CoV-2

Identifiers

PMID34031619
PMCPMC8133493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.