Evidence map›Paper›PMID 34031508›Full record

Trial reportScientific reports2021

Facilitation of oral sensitivity by electrical stimulation of the faucial pillars.

Tobias Braun, Samra Hamzic, Johanna M Doerr, Laura Peters, Maxime Viard, Iris Reuter, Mario Prosiegel, Susanne Weber, Mesut Yenigün, Marlene Tschernatsch and 2 more

Registry-linked trialOpen access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03240965 (Changes in Sensitivity of Swallowing-relevant Structures, Taste and Smell in Stroke Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03240965 recruitingnot on this map

Changes in Sensitivity of Swallowing-relevant Structures, Taste and Smell in Stroke Patients

TypeobservationalSponsorUniversity of GiessenRan2017 to 2026Enrolled200ConditionsDysphagia, StrokeArmsFEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test, Neuropsychological testing
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tobias Braun *Department of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany. tobias.braun@neuro.med.uni-giessen.de.
Samra Hamzic *Department of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Johanna M DoerrDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Laura PetersFaculty of Medicine, Justus-Liebig-University Giessen, Klinikstrasse 29, 35392, Giessen, Germany.
Maxime ViardDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Iris ReuterDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Mario ProsiegelDepartment I, Faculty of Languages and Literatures, Ludwig-Maximilians-University (LMU), Munich, Germany.
Susanne WeberStroke Unit, Buergerhospital Friedberg, Ockstaedter Str. 3-5, 61169, Friedberg, Germany.
Mesut YenigünDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Marlene TschernatschDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Tibo GerrietsDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Martin JuenemannDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
University of Giessen · DEFriedensau Adventist University · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysphagia is common in neurological disease. However, our understanding of swallowing and its central nervous control is limited. Sensory information plays a vital role in the initiation of the swallowing reflex and is often reduced in stroke patients. We hypothesized that the sensitivity threshold of the anterior faucial pillar could be facilitated by either electrical stimulation (ES) or taste and smell information. The sensitivity threshold was measured by ES in the anterior faucial pillar region. The measurement was repeated 5 min after baseline. Thirty minutes after baseline, the participants underwent a test for taste and smell. Immediately after the test, the ES was repeated. Thirty healthy volunteers with a mean age of 27 ± 5.1 participated in the trial. Mean sensitivity threshold at baseline was 1.9 ± 0.59 mA. The values 5 min after baseline (1.74 ± 0.56 mA, p = 0.027) and 30 min after baseline (1.67 ± 0.58 mA, p = 0.011) were significantly lower compared to the baseline, but there was no difference between the latter (p = 0.321). After 5 min, a potentially facilitating effect was found on oral sensitivity by ES of the faucial pillar area. Thirty minutes later, this effect was still present.Trial registration Clinicaltrials.gov, NCT03240965. Registered 7th August 2017- https://clinicaltrials.gov/ct2/show/NCT03240965 .

Indexed as

DeglutitionAdultElectric StimulationFemaleHealthy VolunteersHumansMaleOropharynxYoung Adult

Identifiers

PMID34031508
PMCPMC8144216
OpenAlexW3160134920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.