Evidence map›Paper›PMID 34031499›Full record

ArticleScientific reports2021

Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules.

Eléonore Vissol-Gaudin, Chris Pearson, Chris Groves, Dagou A Zeze, Horacio F Cantiello, María Del Rocio Cantero, Michael C Petty

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eléonore Vissol-GaudinDepartment of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
Chris PearsonDepartment of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
Chris GrovesDepartment of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.ORCID 0000-0003-2402-1618
Dagou A ZezeDepartment of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.ORCID 0000-0002-6596-5490
Horacio F CantielloLaboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.
María Del Rocio CanteroLaboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.
Michael C PettyDepartment of Engineering, Durham University, South Road, Durham, DH1 3LE, UK. m.c.petty@durham.ac.uk.ORCID 0000-0001-5783-678X

Funding

Medical Research Council
6 · The paper itself

Abstract

We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s). The MTs are thought to form a complex electrical network, which can be manipulated with an applied voltage. This feature has been exploited to undertake some experiments on the use of the MT mesh as a medium for computation. We show that it is possible to evolve MT films into binary classifiers following an evolution in materio approach. The accuracy of the system is, on average, similar to that of early carbon nanotube classifiers developed using the same methodology.

Indexed as

AnimalsBrainCattleCells, CulturedMicrotubulesPatch-Clamp TechniquesSpecimen Handling

Identifiers

PMID34031499
PMCPMC8144580

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.