Evidence map›Paper›PMID 34031498›Full record

ArticleScientific reports2021

Association of Candida albicans and Cbp

B A Garcia, N C Acosta, S L Tomar, L F W Roesch, J A Lemos, L R F Mugayar, J Abranches

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. TheApplied and environmental microbiology · 2026
    Article
  3. Identification ofMicroorganisms · 2026
    Article
  4. Silver diamine fluoride for non-operative restorative treatment and prevention of dental caries.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026
    Review
  5. Article
  6. AJournal of bacteriology · 2026
    Review
  7. Artemisinins inhibited the synergistic cariogenic effect betweenFrontiers in cellular and infection microbiology · 2026
    Article
  8. Article
  9. Co-infection with CbpJournal of oral microbiology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Polymicrobial interactions ofJournal of oral microbiology · 2025
    Review
  19. Journal of oral microbiology · 2025
    Article
  20. Microbiome variability and role ofJournal of oral microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

B A Garcia *Department of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, PO Box 100424, Gainesville, FL, 32610, USA.
N C Acosta *Department of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, PO Box 100424, Gainesville, FL, 32610, USA.
S L TomarDepartment of Community Dentistry and Behavioral Science, University of Florida College of Dentistry, Gainesville, FL, USA.
L F W RoeschInterdisciplinary Research Center On Biotechnology-CIP-Biotec, Universidade Federal Do Pampa, São Gabriel, Rio Grande do Sul, Brazil.
J A LemosDepartment of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, PO Box 100424, Gainesville, FL, 32610, USA.
L R F MugayarDepartment of Pediatric Dentistry, University of Florida College of Dentistry, Gainesville, FL, USA.
J AbranchesDepartment of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, PO Box 100424, Gainesville, FL, 32610, USA. jabranches@dental.ufl.edu.
Florida College · USUniversity of Florida · USUniversidade Federal do Pampa · BR

Funding

Intracellular Invasion by Streptococcus mutans: Significance in DiseaseR01DE022559 · NIDCR · UNIVERSITY OF ROCHESTER · PI Jacqueline Abranches, Christine M. Szymanski · 2013 to 2026
$4.8M
Comprehensive Training Program in Oral BiologyR90DE022530 · NIDCR · UNIVERSITY OF FLORIDA · PI LEMOS, JOSE A · 2011 to 2025
$995k
NIDCR NIH HHS 5R90DE022530-09NIDCR NIH HHS DE022559NIDCR NIH HHS R01 DE022559NIDCR NIH HHS R90 DE022530
6 · The paper itself

Abstract

Early childhood caries (ECC) recurrence occurs in approximately 40% of treated cases within one year. The association of Streptococcus mutans and Candida albicans with the onset of ECC is well known. Also, S. mutans strains harboring collagen-binding proteins (Cbps) avidly bind to collagen-rich dentin and are linked to increased caries risk. Here, we investigated the presence of Cbp

Indexed as

Bacterial ProteinsCandida albicansChild, PreschoolCoinfectionCross-Sectional StudiesDental CariesDental Caries SusceptibilityDentinFemaleHumansMaleRecurrenceSalivaStreptococcusStreptococcus mutansBacterial Proteins

Identifiers

PMID34031498
PMCPMC8144385
OpenAlexW3165450467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.