Evidence map›Paper›PMID 34031246›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Bright daytime light enhances circadian amplitude in a diurnal mammal.

Beatriz Bano-Otalora, Franck Martial, Court Harding, David A Bechtold, Annette E Allen, Timothy M Brown, Mino D C Belle, Robert J Lucas

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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  16. Physical activity stimulates clock neurons of the day-active rodentProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Beatriz Bano-OtaloraCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.ORCID 0000-0003-4694-9943
Franck MartialDivision of Neuroscience and Experimental Psychology, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
Court HardingDivision of Neuroscience and Experimental Psychology, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
David A BechtoldCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.ORCID 0000-0001-8676-8704
Annette E AllenCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.ORCID 0000-0003-0214-7076
Timothy M BrownCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
Mino D C BelleInstitute of Biomedical and Clinical Sciences, University of Exeter Medical School, University of Exeter, Exeter EX4 4PS, United Kingdom.ORCID 0000-0002-4917-957X
Robert J LucasCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom robert.lucas@manchester.ac.uk.ORCID 0000-0002-1088-8029
University of Manchester · GBUniversity of Exeter · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P009182/1Biotechnology and Biological Sciences Research Council BB/S01764X/1Wellcome TrustWellcome Trust 210684/Z/18/Z
6 · The paper itself

Abstract

Mammalian circadian rhythms are orchestrated by a master pacemaker in the hypothalamic suprachiasmatic nuclei (SCN), which receives information about the 24 h light-dark cycle from the retina. The accepted function of this light signal is to reset circadian phase in order to ensure appropriate synchronization with the celestial day. Here, we ask whether light also impacts another key property of the circadian oscillation, its amplitude. To this end, we measured circadian rhythms in behavioral activity, body temperature, and SCN electrophysiological activity in the diurnal murid rodent

Indexed as

Circadian RhythmLightAnimalsMammalsNeuronsReproducibility of ResultsSuprachiasmatic Nucleuscircadianlightretinasuprachiasmatic nucleus

Identifiers

PMID34031246
PMCPMC8179182
OpenAlexW3164743632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.