Evidence map›Paper›PMID 34031101›Full record

ArticleeNeuro

Swimming Exercise Promotes Post-injury Axon Regeneration and Functional Restoration through AMPK.

Sandeep Kumar, Sibaram Behera, Atrayee Basu, Shirshendu Dey, Anindya Ghosh-Roy

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Exercise-Induced Differential Transcriptional Output of AMPK Signaling Improves Axon Regeneration and Functional Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  11. Article
  12. Exercise and the Brain: Lessons From Invertebrate Studies.Frontiers in behavioral neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sandeep KumarDepartment of Biotechnology National Brain Research Centre, Manesar 122052, India anindya@nbrc.ac.in sandyjan87@gmail.com.
Sibaram BeheraDepartment of Biotechnology National Brain Research Centre, Manesar 122052, India.
Atrayee BasuDepartment of Biotechnology National Brain Research Centre, Manesar 122052, India.
Shirshendu DeyBruker India Scientific Pvt. Ltd, New Delhi 110019, India.
Anindya Ghosh-RoyDepartment of Biotechnology National Brain Research Centre, Manesar 122052, India anindya@nbrc.ac.in sandyjan87@gmail.com.ORCID 0000-0002-3428-4588
National Brain Research Centre · INBruker (United States) · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Restoration of lost function following a nervous system injury is limited in adulthood as the regenerative capacity of nervous system declines with age. Pharmacological approaches have not been very successful in alleviating the consequences of nervous system injury. On the contrary, physical activity and rehabilitation interventions are often beneficial to improve the health conditions in the patients with neuronal injuries. Using touch neuron circuit of

Indexed as

AxonsCaenorhabditis elegans ProteinsAdultAgedAMP-Activated Protein KinasesAnimalsHumansNerve RegenerationSwimmingAMP-Activated Protein KinasesCaenorhabditis elegans ProteinsAAK-2axon regenerationaxotomyC. elegansPLM neuronswimming exercise

Identifiers

PMID34031101
PMCPMC8211466
OpenAlexW3164254191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.