Evidence map›Paper›PMID 34030812›Full record

ReviewClinics in perinatology2021

Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome.

Elizabeth Sewell, Jessica Roberts, Sagori Mukhopadhyay

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  7. The Critical Period Microbiota Shape Brain Plasticity.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Observational
  10. Impact of gastrostomy tube placement on meningitis in infants with hydrocephalus requiring ventriculoperitoneal shunt.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elizabeth SewellDivision of Neonatology, Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, Office #318, Atlanta, GA 30322, USA.
Jessica RobertsDivision of Neonatology, Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.
Sagori MukhopadhyayDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 800 Spruce Street, 2nd Floor Cathcart Building, Newborn Medicine, Philadelphia, PA, USA. Electronic address: Mukhopadhs@email.chop.edu.
Emory University · USChildren's Hospital of Philadelphia · US

Funding

Incidence of atopy and childhood infections in uninfected term newborns with perinatal antibiotic exposureK23HD088753 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI MUKHOPADHYAY, SAGORI · 2017 to 2021
$790k
NICHD NIH HHS K23 HD088753
6 · The paper itself

Abstract

Perinatal and neonatal infection and associated inflammatory response may adversely affect brain development and lead to neurodevelopmental impairment. Factors that predict the risk of infection and subsequent adverse outcomes have been identified but substantial gaps remain in identifying mechanisms and interventions that can alter outcomes. This article describes the current epidemiology of neonatal sepsis, the pathogenesis of brain injury with sepsis, and the reported long-term neurodevelopment outcomes among survivors.

Indexed as

Enterocolitis, NecrotizingNeonatal SepsisSepsisFemaleHumansInfant, NewbornPregnancyBacteremiaBacterial meningitisCerebral palsyNecrotizing enterocolitis neurodevelopmentNeonatePretermSepsis

Identifiers

PMID34030812
PMCPMC8260078
OpenAlexW3165823812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.