Evidence map›Paper›PMID 34030658›Full record

ArticleBMC infectious diseases2021

Development of a bedside score to predict dengue severity.

Ingrid Marois, Carole Forfait, Catherine Inizan, Elise Klement-Frutos, Anabelle Valiame, Daina Aubert, Ann-Claire Gourinat, Sylvie Laumond, Emilie Barsac, Jean-Paul Grangeon and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Prognostic Models in Patients with Dengue: A Systematic Review.The American journal of tropical medicine and hygiene · 2025
    Pooled it
  2. Article
  3. The Effect of Increased Temperature on Dengue Virus in the VectorTropical medicine and infectious disease · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Ingrid Marois *Internal Medicine and Infectious Diseases Department, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Carole Forfait *Health Authorities (DASS), Noumea, New Caledonia.
Catherine Inizan *Institut Pasteur in New Caledonia, URE Dengue and Arboviruses, Institut Pasteur International Network, Noumea, New Caledonia.
Elise Klement-Frutos *Internal Medicine and Infectious Diseases Department, Territorial Hospital Center (CHT), Dumbea, New Caledonia. elisemma@hotmail.com.ORCID http://orcid.org/0000-0001-6302-3785
Anabelle ValiameHealth Authorities (DASS), Noumea, New Caledonia.
Daina AubertHealth Authorities (DASS), Noumea, New Caledonia.
Ann-Claire GourinatMicrobiology Laboratory, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Sylvie LaumondHealth Authorities (DASS), Noumea, New Caledonia.
Emilie BarsacMicrobiology Laboratory, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Jean-Paul GrangeonHealth Authorities (DASS), Noumea, New Caledonia.
Cécile CazorlaInternal Medicine and Infectious Diseases Department, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Audrey MerletInternal Medicine and Infectious Diseases Department, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Arnaud TarantolaInstitut Pasteur in New Caledonia, URE Epidemiology, Institut Pasteur International Network, Noumea, New Caledonia.
Myrielle Dupont-RouzeyrolInstitut Pasteur in New Caledonia, URE Dengue and Arboviruses, Institut Pasteur International Network, Noumea, New Caledonia.
Elodie Descloux *Internal Medicine and Infectious Diseases Department, Territorial Hospital Center (CHT), Dumbea, New Caledonia.
Centre Hospitalier Territorial de Nouvelle-Calédonie · NCUniversity of New Caledonia · NCInstitut Pasteur de Nouvelle Calédonie · NCSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2017, New Caledonia experienced an outbreak of severe dengue causing high hospital burden (4379 cases, 416 hospital admissions, 15 deaths). We decided to build a local operational model predictive of dengue severity, which was needed to ease the healthcare circuit.

methodsWe retrospectively analyzed clinical and biological parameters associated with severe dengue in the cohort of patients hospitalized at the Territorial Hospital between January and July 2017 with confirmed dengue, in order to elaborate a comprehensive patient's score. Patients were compared in univariate and multivariate analyses. Predictive models for severity were built using a descending step-wise method.

resultsOut of 383 included patients, 130 (34%) developed severe dengue and 13 (3.4%) died. Major risk factors identified in univariate analysis were: age, comorbidities, presence of at least one alert sign, platelets count < 30 × 10

conclusionWe built robust and efficient models to calculate a bedside score able to predict dengue severity in our setting. We propose the spreadsheet for dengue severity score calculations to health practitioners facing dengue outbreaks of enhanced severity in order to improve patients' medical management and hospitalization flow.

Indexed as

DengueFemaleHospitalizationHumansMaleModels, TheoreticalNew CaledoniaPredictive Value of TestsPrognosisRetrospective StudiesRisk FactorsTriageArbovirusesDengueHospital triageOperational toolPacificSeverity score

Identifiers

PMID34030658
PMCPMC8142072
OpenAlexW3108171939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.