ArticleBMC anesthesiology2021
Brain natriuretic peptide and cardiac troponin I for prediction of the prognosis in cancer patients with sepsis.
Article in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Brain natriuretic peptide as a predictive marker of mortality in sepsis: an updated systematic review and meta-analysis.BMC anesthesiology · 2024Pooled it
- Predictive Value of Cardiac Troponin Combined with p-SOFA Score in Sepsis Children with PCIS ≥ 70.International journal of general medicine · 2026Article
- Optimizing Postoperative Analgesia After Perianal Abscess Surgery Using Ultrasound-Guided Pudendal Nerve Block Combined with Wrist-Ankle Acupuncture: A Randomized Controlled Trial.Journal of pain research · 2026Article
- Identification of Prognostic Factors for Sepsis or Septic Shock Patients with Cardiac Dysfunction.Journal of cardiovascular translational research · 2025Article
- Biomarkers to guide sepsis management.Annals of intensive care · 2025Review
- Construction and evaluation of a neonatal septic shock prediction model based on multimodal data.Medicine · 2025Article
- Clinical characteristics and prognostic factors of sepsis in patients with malignancy.Scientific reports · 2025Observational
- Serum S100A12 in the clinical diagnosis of sepsis-induced myocardial dysfunction: an integrated bioinformatics and clinical data analysis.Frontiers in cardiovascular medicine · 2025Article
- Cardiac Troponin I Reveals Diagnostic and Prognostic Superiority to Aminoterminal Pro-B-Type Natriuretic Peptide in Sepsis and Septic Shock.Journal of clinical medicine · 2022Article
- Evaluation Value and Clinical Significance of Cardiac Troponin Level and Pediatric Sequential Organ Failure Score in the Definition of Sepsis 3.0 in Critically Ill Children.Computational and mathematical methods in medicine · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis article aimed to study the value of brain natriuretic peptide (BNP) and cardiac troponin I(cTnI) for predicting the prognosis in cancer patients with sepsis.
methodsA cohort of 233 cancer patients with sepsis admitted to our ICU from January 2017 to October 2020 was included in this retrospective study. The data of BNP and cTnI on the first day (d1) and the third day(d3) after entering ICU, blood lactate (Lac), procalcitonin (PCT), Leucocyte and Sequential Organ failure assessment (SOFA) scores within 24 hr of entering ICU, the incidence of septic shock, acute kidney injury(AKI), acute respiratory failure (ARF) or sepsis-induced myocardial dysfunction(SIMD) in ICU, fluid balance in 24 hr and 72 hr after entering ICU, time of mechanical ventilation(MV), length of stay, emergency surgery were collected. According to 28-day mortality, patients were divided into survival group (190 cases) and death group (43 cases). All the above variables were compared.
resultsBNP was an independent predictor for the mortality in these patients (P < 0.05).While cTnI was not. BNP on d3 in 681.5 pg/ml predicted the mortality with a sensitivity of 91.5 % and a specificity of 88.7 %. All patients were divided into the new two groups following the cutoff value of BNP on d3(681.5pg/ml), and the survival curve showed a significant difference with Kaplan-Meier analysis (P < 0.05). BNP had statistical differences between four groups based on the comorbidities(septic shock, AKI, ARF or SIMD), but cTnI was not.
conclusionsBNP was a great predictor for the prognosis of cancer patients with sepsis, while cTnI was not.
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