Evidence map›Paper›PMID 34030221›Full record

ArticleObstetrics & gynecology science2021

Laterally extended parametrectomy.

Mihai Emil Căpîlna, Lászlo Ungár, Alexandra Lavinia Cozlea, Mihai Gheorghe, Mihai Stanca, Balázs Lintner, Andreea Anamaria Moldovan

Abstract read
In one paragraph

Article in Obstetrics & gynecology science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mihai Emil CăpîlnaFirst Obstetrics and Gynecology Clinic, G. E. Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania.
Lászlo UngárDepartment of Gynecology, Duna Medical Center, Budapest, Hungary.
Alexandra Lavinia CozleaFirst Obstetrics and Gynecology Clinic, G. E. Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania.
Mihai GheorgheFirst Obstetrics and Gynecology Clinic, G. E. Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania.
Mihai StancaFirst Obstetrics and Gynecology Clinic, G. E. Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania.
Balázs LintnerDepartment of Gynecology, Semmelweis University, Budapest, Hungary.
Andreea Anamaria MoldovanDepartment of Infectious Diseases and Epidemiology, County Hospital, Brașov, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the laterally extended parametrectomy (LEP) surgical technique, emphasizing the main challenges of the procedure.

methodsLEP was designed as a more radical surgical procedure aiming to remove the entire parametrial tissue from the pelvic sidewall. Its initial indications were for lymph node positive Stage Ib (current International Federation of Gynecology and Obstetrics 2018 Stage IIIc) and Stage IIb cervical cancer. Currently, with most guidelines recommending definitive radiochemotherapy for these cases, initial LEP indications have become debatable. LEP is now mainly indicated for removing tumors involving the soft structures of the pelvic sidewall during a pelvic exenteration, aiming to obtain lateral free margins. This expands the lateral borders of the dissection to not only the medial surface of internal iliac vessels, but also to the true limits of the pelvic sidewall.

resultsDuring LEP, the parietal and visceral branches of the hypogastric vessels are divided at the entry and exit level of the pelvis. Consequently, the entire internal iliac system is excised, and no connective or lymphatic tissue remain on the pelvic sidewall. The main technical challenges of LEP are caused by the difficulty in ligating large caliber vessels (internal iliac artery and vein) and the variable anatomic distribution of pelvic sidewall veins.

conclusionLEP is a feasible technique for removing pelvic sidewall recurrences, aiming to obtain surgical free margins.

Indexed as

Cervical cancerExcision marginsParametrectomyRecurrences

Identifiers

PMID34030221
PMCPMC8458609

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.