ArticleNature2021
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans.
Open access · bronzeAbstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 328 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
328citing papers in PubMed, 2 pooled it
34.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
328 citing papers in PubMed, 2 syntheses or guidelines pooled it, 567 citations in OpenAlex.
- Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis.Lancet (London, England) · 2023Pooled it
- The Prognostic Value of Pentraxin-3 in COVID-19 Patients: A Systematic Review and Meta-Analysis of Mortality Incidence.International journal of molecular sciences · 2023Pooled it
- Safety and immunogenicity of PHH-1V booster against SARS-CoV-2 variants, including omicron subvariants: Results from a phase IIb open-label extension study.Human vaccines & immunotherapeutics · 2025Trial
- Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants.Scientific reports · 2022Trial
- Integrated Assessment of Humoral and Cellular SARS-CoV-2 Immunity Using ELISA and a Gold Nanoparticle-Based IGRA.International journal of molecular sciences · 2026Article
- The cascade to pathogenicity in autoantibody-mediated CNS diseases.Brain : a journal of neurology · 2026Review
- Longitudinal humoral and memory B-cell responses to repeated SARS-CoV-2 vaccination in long-term care facilities residents.Immunity & ageing : I & A · 2026Article
- First exposure to SARS-CoV-2 shapes IgG subclass switching after mRNA vaccination.Communications medicine · 2026Article
- Long-Term Durability and Dynamics of Anti-S-RBD IgG Response in Healthcare Workers: A Comparative Analysis of Homologous and Heterologous SARS-CoV-2 Vaccination Schedules in a 1-Year Serial Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Multi-omic profiling of human antibody-secreting cells reveals diverse subsets sustain durable humoral immunity.bioRxiv : the preprint server for biology · 2026Article
- The Effects of Past COVID-19 and Vaccination on Antibody Levels, Cellular Immunity, and Cytokine Production by Peripheral Blood Mononuclear Cells.Biomedicines · 2026Article
- A Longitudinal Exploratory Study of SARS-CoV-2 Antibody Dynamics in Young Adults in Bogotá: Lessons from Natural Infection and Post-Vaccination Memory.Biomedicines · 2026Article
- Prospective Biomarkers of SARS-CoV-2 Vaccine Seroconversion in Patients with Haematological Malignancies.Vaccines · 2026Article
- Article
- Host-pathogen interaction in community-acquired pneumonia: a focus on the immune response.Frontiers in cellular and infection microbiology · 2026Review
- Survival after primary and booster COVID-19 vaccination in patients with COPD.Clinical and experimental vaccine research · 2026Article
- A multi-epitope pan-betacoronavirus vaccine construct predicted to induce broad-spectrum and durable immune responses: an immunoinformatics approach.Frontiers in bioinformatics · 2026Article
- Quantification of the IgG antibody response half-life for hybrid immunity to SARS-CoV-2.BMC medicine · 2025Article
- Utilizing wastewater surveillance to model behavioural responses and prevent healthcare overload during "Disease X" outbreaks.Emerging microbes & infections · 2025Article
- Current Status and Challenges of Vaccine Development for Seasonal Human Coronaviruses.Vaccines · 2025Review
268 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Update of
Authors and funding
13 authors at 1 institution in 2 countries.
Jackson S TurnerDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Wooseob KimDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-9199-1000
Elizaveta KalaidinaDivision of Allergy and Immunology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA.
Charles W GossDivision of Biostatistics, Washington University School of Medicine, St Louis, MO, USA.
Adriana M RauseoDivision of Infectious Diseases, Department of lnternal Medicine, Washington University School of Medicine, St Louis, MO, USA.
Aaron J SchmitzDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-8077-6751
Lena HansenDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Alem HaileClinical Trials Unit, Washington University School of Medicine, St Louis, MO, USA.
Michael K KlebertClinical Trials Unit, Washington University School of Medicine, St Louis, MO, USA.
Iskra PusicDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA.
Jane A O'HalloranDivision of Infectious Diseases, Department of lnternal Medicine, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0001-8265-9471
Rachel M PrestiDivision of Infectious Diseases, Department of lnternal Medicine, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-5469-0727
Ali H EllebedyDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. ellebedy@wustl.edu.ORCID http://orcid.org/0000-0002-6129-2532
Washington University in St. Louis · US
Funding
Programming Durable Immune Responses To VaccinationU01AI141990 · NIAID · WASHINGTON UNIVERSITY · PI Ali Hassan Ellebedy · 2019 to 2026
$5.3MNIAID NIH HHS U01 AI141990NIH HHS 1U01 AI150747NIH HHS 5T32 CA009547
Abstract
Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies
Indexed as
AdultAgedBone Marrow CellsCell SurvivalCOVID-19FemaleHumansImmunologic MemoryMaleMiddle AgedPlasma CellsSARS-CoV-2Spike Glycoprotein, CoronavirusYoung AdultSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.