Evidence map›Paper›PMID 34029591›Full record

ArticleThe Journal of biological chemistry2021

Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.

Jeremy J M Liew, Israa M El Saudi, Son V Nguyen, Denyce K Wicht, Daniel P Dowling

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Structural, biophysical, and biochemical insights into C-S bond cleavage by dimethylsulfone monooxygenase.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeremy J M LiewDepartment of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA.
Israa M El SaudiDepartment of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA.
Son V NguyenDepartment of Chemistry and Biochemistry, Suffolk University, Boston, Massachusetts, USA.
Denyce K WichtDepartment of Chemistry and Biochemistry, Suffolk University, Boston, Massachusetts, USA.
Daniel P DowlingDepartment of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA. Electronic address: daniel.dowling@umb.edu.
University of Massachusetts Boston · USSuffolk University · US

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI MALCOLM S. CAPEL · 2018 to 2026
$34.2M
Initiative for Maximizing Student Diversity at UMass BostonR25GM076321 · NIGMS · UNIVERSITY OF MASSACHUSETTS BOSTON · PI COLON-CARMONA, ADAN, SKVIRSKY, RACHEL · 2008 to 2022
$4.5M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
NIGMS NIH HHS P30 GM124165NIGMS NIH HHS R25 GM076321NIH HHS S10 OD021527
6 · The paper itself

Abstract

Bacterial two-component flavin-dependent monooxygenases cleave the stable C-S bond of environmental and anthropogenic organosulfur compounds. The monooxygenase MsuD converts methanesulfonate (MS

Indexed as

Protein MultimerizationAmino Acid SequenceBacterial ProteinsBinding SitesCatalytic DomainFlavin MononucleotideMesylatesMixed Function OxygenasesModels, MolecularPseudomonas fluorescensSubstrate SpecificitySulfurBacterial ProteinsFlavin MononucleotideMesylatesmethanesulfonic acidMixed Function OxygenasesSulfurflavoenzymemethanesulfonateorganosulfursulfur assimilationTIM-barreltwo-component

Identifiers

PMID34029591
PMCPMC8234197
OpenAlexW3164830065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.