Evidence map›Paper›PMID 34029458›Full record

ArticleBioconjugate chemistry2021

A Janus-Type Phthalocyanine for the Assembly of Photoactive DNA Origami Coatings.

Asma Rahali, Ahmed Shaukat, Verónica Almeida-Marrero, Bassem Jamoussi, Andrés de la Escosura, Tomás Torres, Mauri A Kostiainen, Eduardo Anaya-Plaza

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asma RahaliDepartment of Organic Chemistry, Universidad Autónoma de Madrid (UAM), Calle Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Ahmed ShaukatDepartment of Bioproducts and Biosystems, Aalto University, Kemistintie 1, 02150 Espoo, Finland.
Verónica Almeida-MarreroDepartment of Organic Chemistry, Universidad Autónoma de Madrid (UAM), Calle Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Bassem JamoussiDepartment of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
Andrés de la EscosuraDepartment of Organic Chemistry, Universidad Autónoma de Madrid (UAM), Calle Francisco Tomás y Valiente 7, 28049 Madrid, Spain.ORCID 0000-0002-0928-8317
Tomás TorresDepartment of Organic Chemistry, Universidad Autónoma de Madrid (UAM), Calle Francisco Tomás y Valiente 7, 28049 Madrid, Spain.ORCID 0000-0001-9335-6935
Mauri A KostiainenDepartment of Bioproducts and Biosystems, Aalto University, Kemistintie 1, 02150 Espoo, Finland.ORCID 0000-0002-8282-2379
Eduardo Anaya-PlazaDepartment of Bioproducts and Biosystems, Aalto University, Kemistintie 1, 02150 Espoo, Finland.ORCID 0000-0001-9944-6907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Design and synthesis of novel photosensitizer architectures is a key step toward new multifunctional molecular materials. Photoactive Janus-type molecules provide interesting building blocks for such systems by presenting two well-defined chemical functionalities that can be utilized orthogonally. Herein a multifunctional phthalocyanine is reported, bearing a bulky and positively charged moiety that hinders their aggregation while providing the ability to adhere on DNA origami nanostructures via reversible electrostatic interactions. On the other hand, triethylene glycol moieties render a water-soluble and chemically inert corona that can stabilize the structures. This approach provides insight into the molecular design and synthesis of Janus-type sensitizers that can be combined with biomolecules, rendering optically active biohybrids.

Indexed as

NanotechnologyDNAIndolesIsoindolesLightNanostructuresNucleic Acid ConformationStatic ElectricityDNAIndolesIsoindolesphthalocyanine

Identifiers

PMID34029458
PMCPMC8382221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.