Evidence map›Paper›PMID 34029447›Full record

ArticleObesity (Silver Spring, Md.)2021

Obesity and Cancer Risk in White and Black Adults: A Prospective Cohort Study.

Justin C Brown, Shengping Yang, Emily F Mire, Xiaocheng Wu, Lucio Miele, Augusto Ochoa, Jovanny Zabaleta, Peter T Katzmarzyk

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00959270 (Pennington Center Longitudinal), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00959270 recruitingnot on this map

Pennington Center Longitudinal (PCLS)

TypeobservationalSponsorPennington Biomedical Research CenterRan2009 to 2050Enrolled30,000ConditionsHealth Behaviors, Development of Health Problems
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Association of Abdominal Visceral Adiposity and Total Fat Mass with Cancer Incidence and Mortality in White and Black Adults.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Justin C BrownPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID 0000-0001-7540-4913
Shengping YangPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Emily F MirePennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Xiaocheng WuSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Lucio MieleSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Augusto OchoaSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Jovanny ZabaletaSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Peter T KatzmarzykPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID 0000-0002-9280-6022
Pennington Biomedical Research Center · USLouisiana State University Health Sciences Center New Orleans · USLouisiana State Department of Health and Hospitals · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Sujoy Ghosh · 2005 to 2026
$26.5M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
Inflammation, Physical Activity, and Colon Cancer Recurrence and SurvivalR00CA218603 · NCI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BROWN, JUSTIN C · 2019 to 2021
$747k
NCI NIH HHS R00 CA218603NCI NIH HHS R00-CA218603NCI NIH HHS R25 CA203650NCI NIH HHS R25-CA203650NIDDK NIH HHS P30 DK072476NIDDK NIH HHS P30-DK072476NIGMS NIH HHS U54 GM104940NIGMS NIH HHS U54-GM104940
6 · The paper itself

Abstract

objectiveAnthropometric measures of obesity, including BMI and waist circumference (WC), do not quantify excess adiposity and metabolic abnormalities consistently across racial populations. This study tested the hypothesis that participant race modifies the association of anthropometric measures of obesity and cancer risk.

methodsThis prospective cohort (The Pennington Center Longitudinal Study) included 18,296 adults, 6,405 (35.0%) male sex and 6,273 (34.3%) Black race. The primary exposures were BMI (weight in kilograms/height in meters squared) and WC (centimeters). The primary end point was the time from study enrollment to diagnosis of histologically confirmed invasive cancer.

resultsDuring a median follow-up of 14.0 years (interquartile range: 9.8-19.0 years), invasive cancer occurred in 1,350 participants. Among men, race modified the association of BMI (P

conclusionsIn this diverse cohort of adults, participant race and sex modified the prognostic associations of anthropometric measures of obesity and cancer risk.

Indexed as

AdultAgedBlack or African AmericanBody Mass IndexBody WeightCohort StudiesFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedNeoplasmsObesityProspective StudiesRisk Factors

Identifiers

PMID34029447
PMCPMC8422242
OpenAlexW3165478436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.