Evidence map›Paper›PMID 34029326›Full record

ArticlePLoS neglected tropical diseases2021

Detection of cutaneous leishmaniasis in three communities of Oti Region, Ghana.

Richard Akuffo, Carmen Sanchez, Carmen Chicharro, Eugenia Carrillo, Naiki Attram, Mba-Tihssommah Mosore, Clara Yeboah, Nana Konama Kotey, Daniel Boakye, Jose-Antonio Ruiz-Postigo and 4 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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  8. Screening forPathogens (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Richard AkuffoNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0002-5778-1472
Carmen SanchezWHO Collaborating Center for Leishmaniasis, Instituto de Salud Carlos III, Madrid, Spain.
Carmen ChicharroWHO Collaborating Center for Leishmaniasis, Instituto de Salud Carlos III, Madrid, Spain.ORCID 0000-0003-1297-1376
Eugenia CarrilloWHO Collaborating Center for Leishmaniasis, Instituto de Salud Carlos III, Madrid, Spain.
Naiki AttramU.S. Naval Medical Research Unit No. 3, Ghana Detachment, Accra, Ghana.ORCID 0000-0003-0286-1990
Mba-Tihssommah MosoreU.S. Naval Medical Research Unit No. 3, Ghana Detachment, Accra, Ghana.
Clara YeboahU.S. Naval Medical Research Unit No. 3, Ghana Detachment, Accra, Ghana.ORCID 0000-0001-5389-0607
Nana Konama KoteyNational Yaws Control program, Ghana Health Service, Accra, Ghana.
Daniel BoakyeNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0001-6434-7298
Jose-Antonio Ruiz-PostigoDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Javier MorenoWHO Collaborating Center for Leishmaniasis, Instituto de Salud Carlos III, Madrid, Spain.ORCID 0000-0003-0087-4659
Michael WilsonNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0002-6048-8509
Bismark SarfoSchool of Public Health, University of Ghana, Accra, Ghana.ORCID 0000-0002-6995-6364
Francis AntoSchool of Public Health, University of Ghana, Accra, Ghana.
University of Ghana · GHInstituto de Salud Carlos III · ESGhana Health Service · GHWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundCutaneous leishmaniasis (CL) is the most common type of leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some studies in the Volta region have detected Leishmania parasites among persons with skin ulcers. METHODOLOGY/PRINCIPAL

findingsUsing a cross-sectional study design, the prevalence of CL in three communities of the Oti Region of Ghana was investigated. Demographic and epidemiological data were obtained by a structured interviewer administered questionnaire. A total of 426 (12.4%) out of 3,440 participants screened had at least one skin ulcer. Of 595 skin ulcers sampled and tested by PCR for Leishmania infection, 150 (25.2%) ulcers from 136 individuals tested positive, accounting for an overall CL prevalence of 31.9% among persons with skin ulcers. Individual community CL prevalence of 23.2%, 29.8%, and 36.8% was observed in Ashiabre, Keri, and Sibi Hilltop respectively among persons with skin ulcers. CONCLUSIONS/SIGNIFICANCE: Confirmation of CL in the study area suggests an active cycle of transmission of Leishmania infection. The observation of skin ulcers which tested negative to Leishmania infection suggests a need to test for additional causes of skin ulcers such as Treponema pallidum pertenue and Mycobacterium ulcerans in the study area.

Indexed as

AdolescentAdultChildChild, PreschoolCross-Sectional StudiesFemaleGhanaHumansLeishmaniaLeishmaniasis, CutaneousMaleMiddle AgedPolymerase Chain ReactionPrevalenceSkin UlcerSurveys and Questionnaires

Identifiers

PMID34029326
PMCPMC8177633
OpenAlexW3165492747

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.