Evidence map›Paper›PMID 34029145›Full record

ArticleAmerican journal of physiology. Renal physiology2021

Deletion of renal Nedd4-2 abolishes the effect of high K

Yu Xiao, Xin-Peng Duan, Dan-Dan Zhang, Wen-Hui Wang, Dao-Hong Lin

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Thirty years of the NaCl cotransporter: from cloning to physiology and structure.American journal of physiology. Renal physiology · 2023
    Review
  2. Control of sodium and potassium homeostasis by renal distal convoluted tubules.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  3. Kir5.1 channels: potential role in epilepsy and seizure disorders.American journal of physiology. Cell physiology · 2022
    Review
  4. Inwardly rectifying KAmerican journal of physiology. Cell physiology · 2022
    Review
  5. Article
  6. Renal calcium and magnesium handling in Gitelman syndrome.American journal of translational research · 2022
    Review
  7. Article
  8. The effect of high-dietary KFrontiers in physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Yu XiaoDepartment of Physiology, Qiqihar Medical College, Heilongjiang, China.
Xin-Peng DuanDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Dan-Dan ZhangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Dao-Hong LinDepartment of Pharmacology, New York Medical College, Valhalla, New York.ORCID 0000-0003-1760-2684
New York Medical College · US

Funding

Role of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4M
Kir5.1 regulates Kir4.1 ubiquitination by Nedd4-2 in DCTR01DK115366 · NIDDK · NEW YORK MEDICAL COLLEGE · PI LIN, DAO-HONG · 2018 to 2021
$1.5M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR56DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2021 to 2021
$100k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 115366HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 54983
6 · The paper itself

Abstract

High-dietary K

Indexed as

AnimalsBiological TransportIon TransportKidney Tubules, DistalMiceMice, KnockoutNedd4 Ubiquitin Protein LigasesPatch-Clamp TechniquesPotassium Channels, Inwardly RectifyingSolute Carrier Family 12, Member 3Nedd4l protein, mouseNedd4 Ubiquitin Protein LigasesPotassium Channels, Inwardly RectifyingSolute Carrier Family 12, Member 3aldosterone-sensitive distal nephrondistal convoluted tubuleepithelial Na+ channelK+ excretionNa+ transport

Identifiers

PMID34029145
PMCPMC8321800
OpenAlexW3165228724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.