ArticleJournal of medical radiation sciences2021
Visualising the urethra for prostate radiotherapy planning.
Article in Journal of medical radiation sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- The Kilovoltage Intrafraction Monitoring Real-Time Prostate Cancer Image Guided Radiation Therapy Technology Journey: From Clinical Trials to Your Clinic.International journal of radiation oncology, biology, physics · 2026Article
- Dosimetric Clues to Addressing Urinary Toxicity Following Stereotactic Prostate Radiation Therapy.Advances in radiation oncology · 2025Article
- Enhanced urethral identification for radiotherapy planning using fat-suppressed 3D T2-weighted magnetic resonance imaging.Radiological physics and technology · 2025Article
- Developing and validating a simple urethra surrogate model to facilitate dosimetric analysis to predict genitourinary toxicity.Clinical and translational radiation oncology · 2024Article
- Urethra contouring on computed tomography urethrogram versus magnetic resonance imaging for stereotactic body radiotherapy in prostate cancer.Clinical and translational radiation oncology · 2024Article
- Viscous Aqueous Gel Illustrating Natural Anatomy: The VAGINA method in gynaecological MRI simulation.Journal of medical radiation sciences · 2024Article
- Improvement in male pelvis magnetic resonance image contouring following radiologist-delivered training.Journal of medical radiation sciences · 2024Article
- Urethral Interfractional Geometric and Dosimetric Variations of Prostate Cancer Patients: A Study Using an Onboard MRI.Frontiers in oncology · 2022Article
- Visualising the urethra for prostate radiotherapy planning.Journal of medical radiation sciences · 2021Article
- Considerations when introducing MRI into a radiation therapy environment.Journal of medical radiation sciences · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe prostatic urethra is an organ at risk for prostate radiotherapy with genitourinary toxicities a common side effect. Many external beam radiation therapy protocols call for urethral sparing, and with modulated radiotherapy techniques, the radiation dose distribution can be controlled so that maximum doses do not fall within the prostatic urethral volume. Whilst traditional diagnostic MRI sequences provide excellent delineation of the prostate, uncertainty often remains as to the true path of the urethra within the gland. This study aims to assess if a high-resolution isotropic 3D T2 MRI series can reduce inter-observer variability in urethral delineation for radiotherapy planning.
methodsFive independent observers contoured the prostatic urethra for ten patients on three data sets; a 2 mm axial CT, a diagnostic 3 mm axial T2 TSE MRI and a 0.9 mm isotropic 3D T2 SPACE MRI. The observers were blinded from each other's contours. A Dice Similarity Coefficient (DSC) score was calculated using the intersection and union of the five observer contours vs an expert reference contour for each data set.
resultsThe mean DSC of the observer vs reference contours was 0.47 for CT, 0.62 for T2 TSE and 0.78 for T2 SPACE (P < 0.001).
conclusionsThe introduction of a 0.9 mm isotropic 3D T2 SPACE MRI for treatment planning provides improved urethral visualisation and can lead to a significant reduction in inter-observer variation in prostatic urethral contouring.
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