Trial reportAddiction biology2021
Brain imaging of cannabinoid type I (CB
Open access · hybridAbstract readClinical Trial
In one paragraph
Trial report in Addiction biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use disorder.Translational psychiatry · 2023Trial
- Cannabinoid type 1 receptor availability imaging in attention-deficit/hyperactivity disorder using [EJNMMI reports · 2026Article
- Transcriptional Mapping of the Human Cannabinoid Receptor 1 (Molecules (Basel, Switzerland) · 2026Article
- Cannabis use patterns and perception of acute pain during brief abstinence: sex-dependent associations with circulating cannabinoid levels.Psychopharmacology · 2026Article
- PET Molecular Imaging of the Endocannabinoid System in Psychiatric Disorders.Neuroscience bulletin · 2026Review
- Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models.Current topics in behavioral neurosciences · 2026Review
- What Do Thirty Years of Neuroimaging Research Tell Us About Recreational Cannabis Use and Brain Integrity? A Narrative Review of the Multimodal Neuroimaging Evidence to Date.Substance abuse and rehabilitation · 2026Review
- Cannabinoid 1 receptor availability in posttraumatic stress disorder: A positron emission tomography study.Translational psychiatry · 2025Article
- Network topology and cannabis use following two weeks of monitored abstinence: moderation of sex and patterns of use findings.Frontiers in adolescent medicine · 2025Article
- Cannabis use disorder: from neurobiology to treatment.The Journal of clinical investigation · 2024Review
- Fatty Acid Amide Hydrolase and Cannabinoid Receptor Type 1 Genes Regulation is Modulated by Social Isolation in Rats.Neurochemical research · 2024Article
- Effects of acute ΔBrain research · 2024Article
- Clinical and cognitive outcomes in first-episode psychosis: focus on the interplay between cannabis use and genetic variability in endocannabinoid receptors.Frontiers in psychology · 2024Article
- The Relationship Between Circulating Endogenous Cannabinoids and the Effects of Smoked Cannabis.Cannabis and cannabinoid research · 2023Article
- The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses.Psychological medicine · 2023Review
- Sex differences in endocannabinoid tone in a pilot study of cannabis use disorder and acute cannabis abstinence.Addiction biology · 2023Article
- Sex differences in neuroendocrine, sympathetic nervous system, and affect responses to acute stress in cannabis users.Psychopharmacology · 2023Article
- Cannabis Use and Endocannabinoid Receptor Genes: A Pilot Study on Their Interaction on Brain Activity in First-Episode Psychosis.International journal of molecular sciences · 2023Article
- The Inflammatory Signals Associated with Psychosis: Impact of Comorbid Drug Abuse.Biomedicines · 2023Review
- Impact of cyclooxygenase-2 inhibition on cannabis withdrawal and circulating endocannabinoids in daily cannabis smokers.Addiction biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Tory R SpindleDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-2859-116X
Hiroto KuwabaraDivision of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Alisha EversoleDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ayon NandiDivision of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ryan VandreyDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Denis G AntoineDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Annie UmbrichtDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Angela S GuardaDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dean F WongDivision of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Elise M WeertsDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8234-0919
Johns Hopkins University · US
Funding
HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9MIMAGING RESEARCH IN NEUROPSYCHIATRY AND DRUG ABUSEK24DA000412 · NIDA · JOHNS HOPKINS UNIVERSITY · PI WONG, DEAN FOSTER · 2000 to 2009
$1.5MDevelopment of PET radioligands for cerebral cannabinoid receptor (CB1)R33MH079017 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HORTI, ANDREW G · 2009 to 2011
$1.2MDetection Of Drugs Of Abuse In Biological Fluids/TissuesZ01DA000412 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI HUESTIS, MARILYN · 1998 to 2008
$956kCannabinoid PET Imaging in Women Cannabis UsersR21DA043963 · NIDA · JOHNS HOPKINS UNIVERSITY · PI WEERTS, ELISE M, WONG, DEAN FOSTER · 2017 to 2018
$450kDevelopment of PET radioligands for cerebral cannabinoid receptor (CB1)R21MH079017 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HORTI, ANDREW G · 2007 to 2008
$435kIntramural NIH HHS Z01 DA000412NIDA NIH HHS K24 DA000412NIDA NIH HHS R21 DA043963NIDA NIH HHS T32 DA007209NIMH NIH HHS R21 MH079017NIMH NIH HHS R33 MH079017
Abstract
Cannabis effects are predominantly mediated by pharmacological actions on cannabinoid type 1 (CB
Indexed as
AdultAffectAge FactorsBody Mass IndexBrainCravingDouble-Blind MethodFemaleHippocampusHumansMaleMarijuana AbusePatient AcuityPositron-Emission TomographyRadiopharmaceuticalsReceptor, Cannabinoid, CB1RadiopharmaceuticalsReceptor, Cannabinoid, CB1cannabis use disorderPET imagingsex differences
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.