Evidence map›Paper›PMID 34028709›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2021

Advances in Confocal Microscopy and Selected Applications.

W Matt Reilly, Christopher J Obara

Abstract readReview
PubMed Publisher
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Novel Platinum(II) Tetrazine Complex Capable of Live-Cell IEDDA Reaction.Chembiochem : a European journal of chemical biology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Non-invasiveBiomedical optics express · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

W Matt ReillyJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Christopher J ObaraJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. obarac@janelia.hhmi.org.
Howard Hughes Medical Institute · USJanelia Research Campus · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Over the last 30 years, confocal microscopy has emerged as a primary tool for biological investigation across many disciplines. The simplicity of use and widespread accessibility of confocal microscopy ensure that it will have a prominent place in biological imaging for many years to come, even with the recent advances in light sheet and field synthesis microscopy. Since these more advanced technologies still require significant expertise to effectively implement and carry through to analysis, confocal microscopy-based approaches still remain the easiest way for biologists with minimal imaging experience to address fundamental questions about how their systems are arranged through space and time. In this review, we discuss a number of advanced applications of confocal microscopy for probing the spatiotemporal dynamics of biological systems.

Indexed as

AnimalsHumansImage Processing, Computer-AssistedMachine LearningMicroscopy, ConfocalMolecular ImagingProfessional CompetenceSpatio-Temporal AnalysisColocalizationConfocal microscopyDeconvolutionFluorescence correlation spectroscopy (FCS)Fluorescence Lifetime Imaging Microscopy (FLIM)Fluorescence lifetime in photobleaching (FLIP)Fluorescence recovery after photobleaching (FRAP)Hyperspectral imagingImage analysisLinear unmixingMachine learningNeural networkResolutionSuperresolution microscopy

Identifiers

PMID34028709
OpenAlexW3164064269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.