Evidence map›Paper›PMID 34028699›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2021

Insulin Management of Patients with Inadequately Controlled Type 2 Diabetes Admitted to Hospital: Titration Patterns and Frequency of Hypoglycemia as Results of a Prospective Observational Study (Hospital Study).

Jan Brož, Denisa Janíčková Žďárská, Jana Urbanová, Pavlína Piťhová, Viera Doničová, Sabina Pálová, Barbora Pelechová, Anna Smržová, Milan Kvapil

Open access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jan BrožDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic. zorb@seznam.cz.ORCID http://orcid.org/0000-0003-2465-7333
Denisa Janíčková ŽďárskáDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic.
Jana UrbanováDepartment of Internal Medicine, Third Faculty of Medicine and Faculty Hospital Královské Vinohrady, Charles University, Prague, Czech Republic.
Pavlína PiťhováDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic.
Viera DoničováPrivate Department of Diabetology, Internal Medicine and Metabolism, Kosice, Slovakia.
Sabina PálováDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic.
Barbora PelechováDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic.
Anna SmržováInstitute of Biostatistics and Analyses, Ltd., Brno, Czech Republic.
Milan KvapilDepartment of Internal Medicine, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00, Prague, Czech Republic.
Charles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the continuously growing number of therapeutic options for type 2 diabetes mellitus (T2DM) including insulins, a large percentage of patients fail to achieve HbA1c targets. Several real-world studies focused on patients with T2DM receiving insulin treatment in outpatient settings were conducted, but information about real-world in-hospital insulin management is lacking. The aim of this study was to describe the management of insulin therapy with a focus on basal-bolus and premixed insulin regimens in patients with T2DM under routine in-hospital medical practice in the Czech Republic.

methodsThis non-interventional prospective study was conducted from June 2014 to December 2017 in 22 centers in the Czech Republic under routine clinical practice conditions. Adult patients admitted to hospital with metabolically uncontrolled T2DM [HbA1c ≥ 60 mmol/mol; > 7.6% Diabetes Control and Complications Trial (DCCT)] and there treated with basal-bolus and premixed insulin regimens were documented during hospitalization.

resultsOverall, 369 patients with T2DM (54.7% male, mean age 64.44 ± 13.84 years, BMI 31.10 ± 6.00 kg/m

conclusionIn-hospital insulin management regarding basal-bolus and premixed insulin regimens is safe and in concordance with current international recommendations.

Indexed as

Basal-bolus regimenHbA1cHospital insulin managementHypoglycemiaInsulin titrationPremixed insulin regimenType 2 diabetes

Identifiers

PMID34028699
PMCPMC8266977
OpenAlexW3165737625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.