SynthesisActa diabetologica2021
Prevalence of periodontitis in people clinically diagnosed with diabetes mellitus: a meta-analysis of epidemiologic studies.
Synthesis in Acta diabetologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- The Effect of Diabetes on Outcomes of Non-Surgical Periodontal Therapy: A Systematic Review With a Meta-Analysis and Trial Sequential Analysis.International journal of dental hygiene · 2026Pooled it
- Grading the strength and certainty of the scientific evidence of the bidirectional association between periodontitis and noncommunicable diseases: an umbrella review.Evidence-based dentistry · 2025Pooled it
- Prevalence of xerostomia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Poor glycemic control impairs oral health in children with type 1 diabetes mellitus - a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- The efficacy of combining adjuvants with non-surgical periodontal therapy in individuals with type 2 diabetes: A Bayesian network meta-analysis.Journal of clinical periodontology · 2024Pooled it
- Evaluation of a new mouthwash formulated with Chlorhexidine and Cymenol after a scaling and root planing treatment in grade I and II periodontal patients.Medicina oral, patologia oral y cirugia bucal · 2024Trial
- Combined Effect of Nitrate Levels and Diabetes on the Risk of Severe Periodontitis: A Cross-sectional Study.Oral health & preventive dentistry · 2026Article
- Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders.Diabetes, obesity & metabolism · 2026Review
- Oral health and salivary inflammatory markers in children and adolescents with type 1 diabetes: A cross-sectional study.Journal of endocrinological investigation · 2026Article
- Identification of NFKB1, miR-342-5p, -5192, and - 15b as diagnostic biomarkers for periodontitis in type 2 diabetes mellitus: a cross-sectional and experimental study.BMC oral health · 2026Article
- From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis.Frontiers in oral health · 2026Review
- Integrated Strategies for Early Diagnosis and Prevention of Oral Diseases in Asia Pacific.International journal of environmental research and public health · 2025Article
- Single-cell RNA sequencing and Mendelian randomization, revealing molecular mechanisms and causal correlation of immune-related genes in periodontitis.Scientific reports · 2025Article
- Associations Between Glycemic Control, Self-Reported Gingival Bleeding and Lifestyle Factors in Hospitalized Diabetic Patients.Journal of clinical medicine · 2025Article
- Association of Periodontal Status and Porphyromonas gingivalis Concentration with Severity of Coronary Artery Disease in Angiography Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Assessment of oral health status and practice among diabetic and nondiabetic participants.Journal of family medicine and primary care · 2025Article
- Trained immunity: novel perspectives in diabetes and associated complications.Frontiers in immunology · 2025Review
- Exploring the risk factors and clustering patterns of periodontitis in patients with different subtypes of diabetes through machine learning and cluster analysis.Acta odontologica Scandinavica · 2024Article
- An Umbrella Review of the Association Between Periodontal Disease and Diabetes Mellitus.Healthcare (Basel, Switzerland) · 2024Review
- Link between periodontitis and diabetic retinopathy: Inflammatory pathways and clinical implications.World journal of diabetes · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe relationship between diabetes mellitus and periodontitis has long been discussed, but the conclusion of this relationship was controversial. We conducted this meta-analysis to explore the association between diabetes mellitus and the prevalence of periodontitis.
methodsPubMed, Embase, Web of Science, and the Cochrane Library were searched for studies reporting associations of periodontitis with diabetes. Gray literature was integrated from the Open-Gray database. Prevalence estimates and odds ratios were extracted by two independent reviewers and synthesized through meta-analyses.
resultsTwenty-seven papers met the inclusion criteria involving 3092 diabetic patients and 23,494 controls. Overall prevalence of periodontitis was 67.8% in diabetics (combined types) and 35.5% in patients without diabetes (OR, 1.85; 95%CI, 1.61-2.11). Probing depth (MD 0.23; 95% CI, 0.17-0.29; I
conclusionsThe prevalence and severity of periodontitis are greater in patients with diabetes than in non-diabetic populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.