ArticleEuropean child & adolescent psychiatry2022
Genetic factors explain a significant part of associations between adolescent well-being and the social environment.
Article in European child & adolescent psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Social isolation and poor mental health in young people: testing genetic and environmental influences in a longitudinal cohort study.European child & adolescent psychiatry · 2025Article
- Multiple social factors are associated with wellbeing when accounting for shared genetic and environmental confounding.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Disentangling heterogeneity in substance use disorder: Insights from genome-wide polygenic scores.Translational psychiatry · 2024Article
- Bias in Gene-by-Environment Interaction Effects with Sum Scores; An Application to Well-being Phenotypes.Behavior genetics · 2023Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Socio-environmental factors play an important role in adolescent well-being, but potential genetic contributions to these associations are rarely assessed. To address this gap in the literature, associations between well-being and family conflict and functioning, number of friends, friendship importance and satisfaction, and leisure time variables were studied in N = ~ 4700 twin pairs from the Netherlands Twin Register, us ing generalized estimating equations and twin-difference scores. When twin-difference scores indicated a role for genetic factors, we used bivariate genetic models to quantify genetic and environmental contributions to these associations. We identify significant associations between well-being and family functioning, family conflict, different leisure time activities, number of friends, and satisfaction with friendships. Additionally, we find evidence for large (73-91%) genetic influence on the associations between well-being and family conflict and functioning, leisure time sport/scouting clubs, and satisfaction with friendships. Finally, findings support the hypothesis of a causal association between well-being and family conflict and functioning. These findings have important implications for research into the social correlates of well-being in adolescence, as not taking genetic factors into account leads to overestimations of the influence of identified correlates and consequently to recommendations of these correlates as intervention targets.
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Registered trials
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