Evidence map›Paper›PMID 34028586›Full record

ArticleDiabetologia2021

Vitamin D concentrations from neonatal dried blood spots and the risk of early-onset type 2 diabetes in the Danish D-tect case-cohort study.

Amélie Keller, Fanney Thorsteinsdottir, Maria Stougaard, Isabel Cardoso, Peder Frederiksen, Arieh S Cohen, Allan Vaag, Ramune Jacobsen, Berit L Heitmann

Registry-linked trialOpen access · bronzeAbstract readHistorical Article
PubMed Publisher
In one paragraph

Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06509776 (Early Life Determinants of Skeletal Maturation and Endocrine Health in Young Adults - A Nationwide Birth Cohort Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06509776 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Early Life Determinants of Skeletal Maturation and Endocrine Health in Young Adults - A Nationwide Birth Cohort Study

TypeobservationalSponsorHolbaek SygehusRan2024 to 2031Enrolled2,000ConditionsOsteoporosis, Sarcopenia, Obesity, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Vitamin DActa obstetricia et gynecologica Scandinavica · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Amélie KellerResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark. amelie.cleo.keller@regionh.dk.ORCID https://orcid.org/0000-0003-1404-6715
Fanney ThorsteinsdottirResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Maria StougaardResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Isabel CardosoResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Peder FrederiksenResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Arieh S CohenStatens Serum Institute, Clinical Mass Spectrometry, Copenhagen, Denmark.
Allan VaagSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Ramune JacobsenResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Berit L HeitmannResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Frederiksberg Hospital · DKUniversity of Copenhagen · DKStatens Serum Institut · DKSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisThe aim of this study was to examine the influence of neonatal vitamin D concentration on the development of early-onset type 2 diabetes in a large population sample.

methodsWe conducted a case-cohort study utilising data from the Danish biobank and registers. Neonatal vitamin D was assessed measuring 25-hydroxyvitamin D

resultsThe median 25(OH)D CONCLUSIONS/

interpretationThe results of this study do not support the hypothesis that higher neonatal vitamin D concentrations are associated with a lower risk of early-onset type 2 diabetes in adulthood.

Indexed as

Neonatal ScreeningAdultAge of OnsetCase-Control StudiesCohort StudiesDenmarkDiabetes Mellitus, Type 2Dried Blood Spot TestingFemaleFollow-Up StudiesHistory, 20th CenturyHistory, 21st CenturyHumansInfant, NewbornMaleRegistriesVitamin D25(OH)DCase-cohortFetal programmingNeonatalType 2 diabetesVitamin D

Identifiers

PMID34028586
OpenAlexW3164750375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.