Evidence map›Paper›PMID 34027790›Full record

Observational studyThe European journal of general practice2021

Underdiagnosis, false diagnosis and treatment of COPD in a selected population in Northern Greece.

Dionisios Spyratos, Diamantis Chloros, Dionisia Michalopoulou, Ioanna Tsiouprou, Konstantinos Christoglou, Lazaros Sichletidis

Registry-linked trialOpen access · goldAbstract readLetterObservational Study
In one paragraph

Observational study in The European journal of general practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07543601 (Enhanced COPD Management in Suspected Lung Cancer Patients - Improving Outcomes Through Timely Intervention), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07543601 narecruitingnot on this mapstarted 2026, after this paper: background citation

Enhanced COPD Management in Suspected Lung Cancer Patients - Improving Outcomes Through Timely Intervention

TypeinterventionalSponsorDitte Krag-HansenRan2026 to 2027Enrolled280ConditionsCOPD (Chronic Obstructive Pulmonary Disease), Lung Cancer (Diagnosis), Lung Neoplasm Malignant, Lung CarcinomaArmsTailored COPD consultations
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Truth and Consequences: Choosing the Best Interpretative Framework for Spirometry.American journal of respiratory and critical care medicine · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Dionisios SpyratosPulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
Diamantis ChlorosPulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
Dionisia MichalopoulouPrimary Care Center, Municipality of Thessaloniki, Thessaloniki, Greece.
Ioanna TsiouprouPulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
Konstantinos Christoglou3rd Regional Health Care Authority, Thessaloniki, Greece.
Lazaros SichletidisPulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRHellenic Agency for Local Development and Local Government · GRRegional Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the primary care setting, diagnosis and treatment of COPD is not always consistent with GOLD guidelines.

objectivesTo calculate the prevalence of COPD underdiagnosis, false diagnosis and treatment in the general population of northern Greece.

methodsObservational study in the context of an early COPD detection and smoking cessation project. Inclusion criteria: >40-year-old, current and former smokers (>10 pack-years) in five primary care centres of northern Greece from 2012 to 2019. Participation was achieved

resultsWe examined 5,226 subjects (mean age: 58.2 ± 12.7 years, 61.5% males, current smokers: 56.2%) of whom 564 (10.8%) had symptoms and spirometrically confirmed COPD. There were 5 groups of 'interest:'

conclusionAmong the general population subjects in northern Greece, more than 50% of patients with COPD were underdiagnosed, more than 50% of correctly diagnosed COPD patients were overtreated and most patients taking inhaled drugs were those with a false diagnosis of COPD (possibly GOLD stage 0).

Indexed as

Pulmonary Disease, Chronic ObstructiveAdultAgedBronchodilator AgentsFemaleGreeceHumansMaleMedical OveruseMiddle AgedSpirometryBronchodilator AgentsCOPD diagnosisfalse diagnosisovertreatmentPrimary careunderdiagnosis

Identifiers

PMID34027790
PMCPMC8158270
OpenAlexW3165795639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.