Evidence map›Paper›PMID 34027634›Full record

ArticleYonsei medical journal2021

Incidence and Clinical Outcomes of Febrile Neutropenia in Adult Cancer Patients with Chemotherapy Using Korean Nationwide Health Insurance Database.

Dalyong Kim, Soohyeon Lee, Taemi Youk, Soojung Hong

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Dalyong Kim *Division of Hematology & Medical Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0003-0193-422X
Soohyeon Lee *Division of Oncology/Hematology, Department of Internal Medicine, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0001-9665-062X
Taemi YoukDepartment of Statistics, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0002-4273-3777
Soojung HongDivision of Oncology-Hematology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea. suzzy901@nhimc.or.kr.ORCID https://orcid.org/0000-0002-4350-2794
Dongguk University Ilsan Hospital · KRKorea University · KRNational Health Insurance Service Ilsan Hospital · KRStatistics Korea · KR

Funding

National Health Insurance Service Ilsan Hospital NHIS-2015-20-018
6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the episodes of febrile neutropenia (FN) in patients with gastric cancer (GC), colorectal cancer (CRC), lung cancer (LC), and breast cancer (BC); and to identify the incidence and trends of admission rates, as well as factors affecting mortality. MATERIALS AND

methodsUsing nationwide claims data, all new admissions to hospitals for FN were selected. We evaluated the incidence of FN and mortality-related clinical factors in adult cancer patients who received cytotoxic chemotherapy from January 2004 to December 2013.

resultsWhile the incidence of FN increased, the length of hospitalization decreased in Korea. The incidence of FN was 19.8% in LC patients, 15.5% in GC patients, 13.3% in BC patients, and 9.5% in CRC patients. The overall in-hospital mortality of FN was 12.9% and showed a decreasing trend. Admission rates to intensive care units and in-hospital mortality were the highest for lung cancer (15.2% and 19.3%, respectively). Age and sepsis syndrome were risk factors for in-hospital mortality for all cancer types.

conclusionCareful observation and active prophylaxis should be considered for patients at high risk of FN.

Indexed as

Breast NeoplasmsFebrile NeutropeniaAdultAntineoplastic Combined Chemotherapy ProtocolsHumansIncidenceInsurance, HealthRepublic of KoreaRetrospective StudiesRisk FactorsChemotherapyfebrile neutropenianational health insurance

Identifiers

PMID34027634
PMCPMC8149937
OpenAlexW3164423874

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.