Evidence map›Paper›PMID 34027617›Full record

ArticleIntensive care medicine experimental2021

Continuous intra-gastral monitoring of intra-abdominal pressure in critically ill children: a validation study.

T Kaussen, M Gutting, F Lasch, D Boethig, A von Gise, J Dingemann, H Koeditz, T Jack, M Sasse, P Beerbaum and 1 more

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

T Kaussen *Department of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany. Kaussen.torsten@mh-hannover.de.ORCID http://orcid.org/0000-0003-1385-362X
M Gutting *Department of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
F LaschInstitute of Biometry, Hannover Medical School, Hannover, Germany.
D BoethigDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
A von GiseDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
J DingemannDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
H KoeditzDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
T JackDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
M SasseDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
P BeerbaumDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
M BoehneDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn critically ill children, detection of intra-abdominal hypertension (IAH > 10 mmHg) and abdominal compartment syndrome (ACS = IAH + organ dysfunction) is paramount and usually monitored through intra-vesical pressures (IVP) as current standard. IVP, however, carries important disadvantages, being time-consuming, discontinuous, with infection risk through observer-dependent manipulation, and ill-defined for catheter sizes. Therefore, we sought to validate air-capsule-based measurement of intra-gastric pressure (ACM-IGP).

methodsWe prospectively compared ACM-IGP with IVP both in vivo and in vitro (water column), according to Abdominal-Compartment-Society validation criteria. We controlled for patient age, admission diagnosis, gastric filling/propulsive medication, respiratory status, sedation levels and transurethral catheters, all influencing intra-abdominal pressure (IAP).

resultsIn tertiary care PICU setting, finally, n = 97 children were enrolled (median age, 1.3 years [range 0 days-17 years], LOS-PICU 8.0 [1-332] days, PRISM-III-Score 13 [0-35]). In n = 2.770 measurements pairs, median IAP was 6.7 [0.9-23.0] mmHg, n = 38 (39%) children suffered from IAH > 10 mmHg, n = 4 from ACS. In vitro against water column, ACM-IGP correlated perfectly (r

conclusionsIn a large PICU population with high IAH prevalence, ACM-IGP agreed favourably with IVP. More widespread usage of ACM-IGP may improve detection rates of ACS in critically ill children. Trial registration WHO-ICTRP-No. DRKS00006556 (German Clinical Trial Register). Registered 12th September 2014, URL: https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00006556.

Indexed as

Abdominal compartment syndromeAir capsule nasogastric tubeIntra-abdominal hypertensionIntra-abdominal pressure measurementIntra-gastric pressure measurementPaediatric intensive care

Identifiers

PMID34027617
PMCPMC8141480
OpenAlexW3112217632

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.