Evidence map›Paper›PMID 34027574›Full record

ArticleNeurosurgical review2022

In vitro testing of explanted shunt valves in hydrocephalic patients with suspected valve malfunction.

Christoph Bettag, Christian von der Brelie, Florian Baptist Freimann, Ulrich-Wilhelm Thomale, Veit Rohde, Ingo Fiss

Abstract read
In one paragraph

Article in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christoph BettagDepartment of Neurosurgery, Georg-August-Universität Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany. christoph.bettag@med.uni-goettingen.de.ORCID http://orcid.org/0000-0001-6450-6201
Christian von der BrelieDepartment of Neurosurgery, Georg-August-Universität Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Florian Baptist FreimannDepartment of Neurosurgery, Georg-August-Universität Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Ulrich-Wilhelm ThomalePediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.
Veit RohdeDepartment of Neurosurgery, Georg-August-Universität Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Ingo FissDepartment of Neurosurgery, Georg-August-Universität Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of symptomatic valve malfunction in hydrocephalic patients treated with VP-Shunt (VPS) might be difficult. Clinical symptoms such as headache or nausea are nonspecific, hence cerebrospinal fluid (CSF) over- or underdrainage can only be suspected but not proven. Knowledge concerning valve malfunction is still limited. We aim to provide data on the flow characteristics of explanted shunt valves in patients with suspected valve malfunction. An in vitro shunt laboratory setup was used to analyze the explanted valves under conditions similar to those in an implanted VPS. The differential pressure (DP) of the valve was adjusted stepwise to 20, 10, 6, and 4 cmH

Indexed as

HydrocephalusCerebrospinal Fluid ShuntsHumansIn Vitro TechniquesMaleProstheses and ImplantsSoftwareVentriculoperitoneal ShuntHydrocephalusShunt failureShunt valveVentriculo peritoneal shunt

Identifiers

PMID34027574
PMCPMC8827297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.