Evidence map›Paper›PMID 34027446›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2021

Patterns of Articular Cartilage Thickness in Pediatric and Adolescent Knees: A Magnetic Resonance Imaging-Based Study.

Sreetha Sidharthan, Annie Yau, Bryan Aristega Almeida, Kevin G Shea, Harry G Greditzer, Kristofer J Jones, Peter D Fabricant

Open access · goldAbstract read
In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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  9. [Patellar cartilage repair-current concepts and evidence].Orthopadie (Heidelberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sreetha SidharthanDivisions of Pediatric Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, U.S.A.
Annie YauDivisions of Pediatric Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, U.S.A.
Bryan Aristega AlmeidaDivisions of Pediatric Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, U.S.A.
Kevin G SheaStanford University School of Medicine, Stanford, California, U.S.A.
Harry G GreditzerRadiology & Imaging, Hospital for Special Surgery, New York, New York, U.S.A.
Kristofer J JonesDavid Geffen School of Medicine at UCLA, Los Angeles, California, U.S.A.
Peter D FabricantDivisions of Pediatric Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, U.S.A.
Hospital for Special Surgery · USStanford University · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for any associations with age and skeletal maturity.

methodsMRI scans were analyzed in patients 7 to 18 years old without osteochondral lesions, chondral wear/pathology, intra-articular fractures, or history of knee surgery. Measurements of articular cartilage thickness at the patella (medial facet, lateral facet, median ridge), femur (medial condyle, lateral condyle, lateral trochlea), and tibia (medial plateau, lateral plateau) were made on axial, coronal, and sagittal MRI. Descriptive statistics were used to calculate mean cartilage thickness by age and sex. Analysis of variance with repeated measures, analysis of covariance, independent samples

resultsA total of 240 knee MRI scans were included. Articular cartilage was thickest at the patella and did not vary with age or skeletal maturity. On the femur, articular cartilage was thickest at the lateral trochlea with mean cartilage thickness of 4.4 ± 1.4 mm in male patients and 3.6 ± 1.3 mm in female patients (

conclusionsIn pediatric and adolescent knees, articular cartilage is thickest at the patella, where it does not strongly correlate with age. In contrast, there is a strong inverse association between increasing age and articular cartilage thickness of the distal femoral condyles. CLINICAL RELEVANCE: The longitudinal reference data presented in this study can aid in pre-operative interpretation of knee cartilage under pathologic conditions in pediatric and adolescent patients.

Identifiers

PMID34027446
PMCPMC8128992
OpenAlexW3127295516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.