ArticleCJC open2021
Screening for Obstructive Sleep Apnea in an Atrial Fibrillation Population: What's the Best Test?
Article in CJC open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Relationship between Positional Obstructive Sleep Apnea and Excessive Daytime Sleepiness in Patients with Atrial Fibrillation.Sleep and biological rhythms · 2026Article
- Sleep Apnea and Cardiovascular Disease: Risks, Mechanisms, Complications, and Management.Reviews in cardiovascular medicine · 2026Review
- Screening obstructive sleep apnea using clinical questionnaires and the triglyceride-glucose index: a cardiovascular risk-based approach.NPJ primary care respiratory medicine · 2026Article
- Impact of obstructive sleep apnea on arrhythmic risk in ischemic heart disease and hypertrophic cardiomyopathy: insights from a large national cohort.Frontiers in cardiovascular medicine · 2026Article
- Validation and implementation of ambulatory obstructive sleep apnea polygraphy screening combined with wearable semi-continuous heart rhythm monitoring in patients with atrial fibrillation: a validation and a pilot study.Frontiers in cardiovascular medicine · 2026Article
- Prevalence and Diagnosis of Obstructive Sleep Apnea in Atrial Fibrillation Patients: A Systematic Review.Journal of clinical medicine · 2025Review
- Atrial fibrillation-specific refinement of the STOP-Bang sleep apnoea screening questionnaire: insights from the Virtual-SAFARI study.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea.Experimental biology and medicine (Maywood, N.J.) · 2022Review
- Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity.Advances in experimental medicine and biology · 2022Review
- Cardiorespiratory Polygraphy for Detection of Obstructive Sleep Apnea in Patients With Atrial Fibrillation.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmong individuals with nonvalvular atrial fibrillation (AF), the prevalence of obstructive sleep apnea (OSA) can be as high as 85%. Continuous positive airway pressure treatment for moderate or severe OSA might improve AF outcomes and quality of life, so early identification of OSA might be of value. However, screening questionnaires for OSA are suboptimal because they are weighted toward tiredness and loud snoring, which might be absent in AF patients. NoSAS (
methodsWe prospectively compared the accuracy of the NoSAS, the STOP-BANG questionnaire (
resultsOf 188 participants, 86% had OSA and 49% had moderate or severe OSA. Mean Epworth Sleepiness Scale scores were low; 5.9 (SD, 3.9), indicating that most participants were not sleepy. Receiver operating characteristic curves for comparisons of screening tests with HSAT showed suboptimal accuracy. For moderate plus severe and severe only groups respectively, the area under the curve was 0.50 (95% confidence interval [CI], 0.42-0.58) and 0.42 (95% CI, 0.34-0.52) for AP, 0.65 (95% CI, 0.58-0.73) and 0.63 (95% CI, 0.52-0.74) for the STOP-BANG questionnaire, and 0.68 (95% CI, 0.60-0.75) and 0.69 (95% CI, 0.59-0.80) for the NoSAS.
conclusionsAP and NoSAS are not sufficiently accurate for screening AF patients for OSA. Because of the high rates of OSA in this cohort, the potential benefits of OSA treatment, and the suboptimal accuracy of current screening questionnaires, cardiologists should consider HSAT for AF patients.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.