Evidence map›Paper›PMID 34027240›Full record

ArticleBioactive materials2021

Ionized jet deposition of antimicrobial and stem cell friendly silver-substituted tricalcium phosphate nanocoatings on titanium alloy.

Gabriela Graziani, Katia Barbaro, Inna V Fadeeva, Daniele Ghezzi, Marco Fosca, Enrico Sassoni, Gianluca Vadalà, Martina Cappelletti, Francesco Valle, Nicola Baldini and 1 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Gabriela GrazianiIRCSS Istituto Ortopedico Rizzoli, Laboratory of NanoBiotechnology, via di Barbiano 1/10 40136, Bologna, Italy.
Katia BarbaroIstituto Zooprofilattico Sperimentale Lazio e Toscana "M. Aleandri", Via Appia Nuova 1411-00178, Rome, Italy.
Inna V FadeevaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky prospect 49, 119334, Moscow, Russia.
Daniele GhezziIRCSS Istituto Ortopedico Rizzoli, Laboratory of NanoBiotechnology, via di Barbiano 1/10 40136, Bologna, Italy.
Marco FoscaIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere, 100 - 00133, Rome, Italy.
Enrico SassoniUniversity of Bologna, Department of Civil, Chemical, Environmental and Materials Engineering, via Terracini 28 40131, Bologna, Italy.
Gianluca VadalàUniversità Campus Bio-Medico di Roma, Research Unit of Orthopaedic Surgery, Faculty of Medicine and Surgery, Via Alvaro del Portillo 21, 00128, Rome, Italy.
Martina CappellettiUniversity of Bologna, Department of Pharmacy and Biotechnology, via Irnerio 42, 40126, Bologna, Italy.
Francesco ValleInstitute of Nanostructured Materials, National Research Council (ISMN-CNR), Via Piero Gobetti, 101, 40129, Bologna, Italy.
Nicola BaldiniIRCSS Istituto Ortopedico Rizzoli, Laboratory of NanoBiotechnology, via di Barbiano 1/10 40136, Bologna, Italy.
Julietta V RauIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere, 100 - 00133, Rome, Italy.
Istituto Ortopedico Rizzoli · ITUniversity of Bologna · ITBaikov Institute of Metallurgy and Materials Science · RUInstitute of Nanostructured Materials · ITInstitute of Structure of Matter · ITIstituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana · ITSechenov University · RUUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthopedic infections pose severe societal and economic burden and interfere with the capability of the implanted devices to integrate in the host bone, thus significantly increasing implants failure rate. To address infection and promote integration, here nanostructured antibacterial and bioactive thin films are proposed, obtained, for the first time, by Ionized Jet Deposition (IJD) of silver-substituted tricalcium phosphate (Ag-TCP) targets on titanium. Coatings morphology, composition and mechanical properties are characterized and proof-of-concept of biocompatibility is shown. Antimicrobial efficacy is investigated against four Gram positive and Gram negative bacterial strains and against

Indexed as

Antibacterial ceramicsAntibacterial coatingsNanostructured coatingsOrthopedicsSilverTricalcium phosphate

Identifiers

PMID34027240
PMCPMC8121618
OpenAlexW3119559501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.