Evidence map›Paper›PMID 34027218›Full record

ArticleArchives of medical sciences. Atherosclerotic diseases2021

Prevalence and risk factors for the development of abdominal aortic calcification among the US population: NHANES study.

Ebad Ur Rahman, Muchi Ditah Chobufo, Fatima Farah, Adee Elhamdani, Arfaat Khan, Ellen A Thompson, Wilbert S Aronow, Mehiar El-Hamdani

Open access · diamondAbstract read
In one paragraph

Article in Archives of medical sciences. Atherosclerotic diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Ebad Ur RahmanDepartment of Internal Medicine, St Mary's Medical Center, Huntington, USA.
Muchi Ditah ChobufoDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn NY, USA.
Fatima FarahDepartment of Medicine, Deccan College of Medical Sciences, Hyderabad, India.
Adee ElhamdaniAllegheny Health Network, Pittsburgh, USA.
Arfaat KhanHenry Ford Health System, Detroit, MI, USA.
Ellen A ThompsonDepartment of Cardiology, Marshall University, Huntington, WV, USA.
Wilbert S AronowDepartment of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA.
Mehiar El-HamdaniDepartment of Cardiology, Marshall University, Huntington, WV, USA.
Marshall University · USAllegheny Health Network · USDeccan College of Medical Sciences · INHenry Ford Health System · USInterfaith Medical Center · USNew York Medical College · USSt. Mary's Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAbdominal aortic calcification (AAC) is an important marker of subclinical cardiovascular disease and its prognosis. Advanced age, hypertension, smoking, dyslipidemia, diabetes mellitus, and higher truncal fat are known markers of AAC in studies conducted around the world. However, literature for these risk factors and their co-occurrence is limited in the US. MATERIAL AND

methodsWe used data from dual energy X-ray absorptiometry (Hologic, v4.0) to detect the occurrence of AAC in a sample population (

resultsWe found the national prevalence of AAC in the US to be 28.8%. After adjusting for confounders, persons with hypertension: OR = 1.66 (95% CI: 1.30-2.13) and smokers: OR = 1.63 (95% CI: 1.24-2.14) were more likely to have AAC compared to their respective counterparts. Increasing age was positively associated with AAC: OR = 1.06 (95% CI: 1.04-1.08). There was a statistically significant negative association between body mass index (BMI) and AAC, more so in smokers than in non-smokers: OR = 0.97 (95% CI: 0.94-0.97). We did not observe any statistically significant association between diabetes and AAC.

conclusionsAdvanced age, smoking, and hypertension was associated with increased occurrence of AAC. Paradoxically, increasing BMI was inversely associated with AAC and there was no statistically significant association between total body and trunk fat percentages and AAC. To the best of our knowledge, this is the first study to establish the nationwide prevalence and associated factors in the US.

Indexed as

abdominal aortic calcificationNHANES databaseprevalencerisk factors

Identifiers

PMID34027218
PMCPMC8117070
OpenAlexW3158827210

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.